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Targeting cancer stem cell OXPHOS with tailored ruthenium complexes as a new anti-cancer strategy.
Alcalá S, Villarino L, Ruiz-Cañas L, Couceiro JR, Martínez-Calvo M, Palencia-Campos A, Navarro D, Cabezas-Sainz P, Rodriguez-Arabaolaza I, Cordero-Barreal A, Trilla-Fuertes L, Rubiolo JA, Batres-Ramos S, Vallespinos M, González-Páramos C, Rodríguez J, Gámez-Pozo A, Vara JÁF, Fernández SF, Berlinches AB, Moreno-Mata N, Redondo AMT, Carrato A, Hermann PC, Sánchez L, Torrente S, Fernández-Moreno MÁ, Mascareñas JL, Sainz B Jr. Alcalá S, et al. Among authors: gonzalez paramos c. J Exp Clin Cancer Res. 2024 Jan 27;43(1):33. doi: 10.1186/s13046-023-02931-7. J Exp Clin Cancer Res. 2024. PMID: 38281027 Free PMC article.
Distinct GSDMB protein isoforms and protease cleavage processes differentially control pyroptotic cell death and mitochondrial damage in cancer cells.
Oltra SS, Colomo S, Sin L, Pérez-López M, Lázaro S, Molina-Crespo A, Choi KH, Ros-Pardo D, Martínez L, Morales S, González-Paramos C, Orantes A, Soriano M, Hernández A, Lluch A, Rojo F, Albanell J, Gómez-Puertas P, Ko JK, Sarrió D, Moreno-Bueno G. Oltra SS, et al. Among authors: gonzalez paramos c. Cell Death Differ. 2023 May;30(5):1366-1381. doi: 10.1038/s41418-023-01143-y. Epub 2023 Mar 11. Cell Death Differ. 2023. PMID: 36899106 Free PMC article.
Metformin reduces macrophage HIF1α-dependent proinflammatory signaling to restore brown adipocyte function in vitro.
Pescador N, Francisco V, Vázquez P, Esquinas EM, González-Páramos C, Valdecantos MP, García-Martínez I, Urrutia AA, Ruiz L, Escalona-Garrido C, Foretz M, Viollet B, Fernández-Moreno MÁ, Calle-Pascual AL, Obregón MJ, Aragonés J, Valverde ÁM. Pescador N, et al. Among authors: gonzalez paramos c. Redox Biol. 2021 Oct 19;48:102171. doi: 10.1016/j.redox.2021.102171. Online ahead of print. Redox Biol. 2021. PMID: 34736121 Free PMC article.
c-Src functionality controls self-renewal and glucose metabolism in MCF7 breast cancer stem cells.
Mayoral-Varo V, Calcabrini A, Sánchez-Bailón MP, Martínez-Costa ÓH, González-Páramos C, Ciordia S, Hardisson D, Aragón JJ, Fernández-Moreno MÁ, Martín-Pérez J. Mayoral-Varo V, et al. Among authors: gonzalez paramos c. PLoS One. 2020 Jul 16;15(7):e0235850. doi: 10.1371/journal.pone.0235850. eCollection 2020. PLoS One. 2020. PMID: 32673341 Free PMC article.
Generation of a human iPSC line from a patient with Leigh syndrome.
Galera T, Zurita F, González-Páramos C, Moreno-Izquierdo A, Fraga MF, Fernández AF, Garesse R, Gallardo ME. Galera T, et al. Among authors: gonzalez paramos c. Stem Cell Res. 2016 Jan;16(1):63-6. doi: 10.1016/j.scr.2015.12.005. Epub 2015 Dec 12. Stem Cell Res. 2016. PMID: 27345786 Free article.
Cardiac dysfunction in mitochondrial disease. Clinical and molecular features.
Villar P, Bretón B, García-Pavía P, González-Páramos C, Blázquez A, Gómez-Bueno M, García-Silva T, García-Consuegra I, Martín MA, Garesse R, Bornstein B, Gallardo ME. Villar P, et al. Among authors: gonzalez paramos c. Circ J. 2013;77(11):2799-806. doi: 10.1253/circj.cj-13-0557. Epub 2013 Aug 20. Circ J. 2013. PMID: 23965802 Free article.