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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 2
2003 2
2004 4
2005 2
2006 2
2007 1
2008 1
2009 1
2013 2
2015 1
2016 1
2024 0

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18 results

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Page 1
Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer.
Root AR, Cao W, Li B, LaPan P, Meade C, Sanford J, Jin M, O'Sullivan C, Cummins E, Lambert M, Sheehan AD, Ma W, Gatto S, Kerns K, Lam K, D'Antona AM, Zhu L, Brady WA, Benard S, King A, He T, Racie L, Arai M, Barrett D, Stochaj W, LaVallie ER, Apgar JR, Svenson K, Mosyak L, Yang Y, Chichili GR, Liu L, Li H, Burke S, Johnson S, Alderson R, Finlay WJJ, Lin L, Olland S, Somers W, Bonvini E, Gerber HP, May C, Moore PA, Tchistiakova L, Bloom L. Root AR, et al. Among authors: somers w. Antibodies (Basel). 2016 Mar 4;5(1):6. doi: 10.3390/antib5010006. Antibodies (Basel). 2016. PMID: 31557987 Free PMC article.
Atypical antigen recognition mode of a shark immunoglobulin new antigen receptor (IgNAR) variable domain characterized by humanization and structural analysis.
Kovalenko OV, Olland A, Piché-Nicholas N, Godbole A, King D, Svenson K, Calabro V, Müller MR, Barelle CJ, Somers W, Gill DS, Mosyak L, Tchistiakova L. Kovalenko OV, et al. Among authors: somers w. J Biol Chem. 2013 Jun 14;288(24):17408-19. doi: 10.1074/jbc.M112.435289. Epub 2013 Apr 30. J Biol Chem. 2013. PMID: 23632026 Free PMC article.
Triad of polar residues implicated in pH specificity of acidic mammalian chitinase.
Olland AM, Strand J, Presman E, Czerwinski R, Joseph-McCarthy D, Krykbaev R, Schlingmann G, Chopra R, Lin L, Fleming M, Kriz R, Stahl M, Somers W, Fitz L, Mosyak L. Olland AM, et al. Among authors: somers w. Protein Sci. 2009 Mar;18(3):569-78. doi: 10.1002/pro.63. Protein Sci. 2009. PMID: 19241384 Free PMC article.
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
Mosyak L, Georgiadis K, Shane T, Svenson K, Hebert T, McDonagh T, Mackie S, Olland S, Lin L, Zhong X, Kriz R, Reifenberg EL, Collins-Racie LA, Corcoran C, Freeman B, Zollner R, Marvell T, Vera M, Sum PE, Lavallie ER, Stahl M, Somers W. Mosyak L, et al. Among authors: somers w. Protein Sci. 2008 Jan;17(1):16-21. doi: 10.1110/ps.073287008. Epub 2007 Nov 27. Protein Sci. 2008. PMID: 18042673 Free PMC article.
The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition.
Mosyak L, Wood A, Dwyer B, Buddha M, Johnson M, Aulabaugh A, Zhong X, Presman E, Benard S, Kelleher K, Wilhelm J, Stahl ML, Kriz R, Gao Y, Cao Z, Ling HP, Pangalos MN, Walsh FS, Somers WS. Mosyak L, et al. Among authors: somers ws. J Biol Chem. 2006 Nov 24;281(47):36378-90. doi: 10.1074/jbc.M607314200. Epub 2006 Sep 27. J Biol Chem. 2006. PMID: 17005555 Free article.
A novel approach to identifying beta-secretase inhibitors: bis-statine peptide mimetics discovered using structure and spot synthesis.
Bridges KG, Chopra R, Lin L, Svenson K, Tam A, Jin G, Cowling R, Lovering F, Akopian TN, DiBlasio-Smith E, Annis-Freeman B, Marvell TH, LaVallie ER, Zollner RS, Bard J, Somers WS, Stahl ML, Kriz RW. Bridges KG, et al. Among authors: somers ws. Peptides. 2006 Jul;27(7):1877-85. doi: 10.1016/j.peptides.2006.02.003. Epub 2006 Mar 30. Peptides. 2006. PMID: 16574278
Use of structure-based drug design approaches to obtain novel anthranilic acid acyl carrier protein synthase inhibitors.
Joseph-McCarthy D, Parris K, Huang A, Failli A, Quagliato D, Dushin EG, Novikova E, Severina E, Tuckman M, Petersen PJ, Dean C, Fritz CC, Meshulam T, DeCenzo M, Dick L, McFadyen IJ, Somers WS, Lovering F, Gilbert AM. Joseph-McCarthy D, et al. Among authors: somers ws. J Med Chem. 2005 Dec 15;48(25):7960-9. doi: 10.1021/jm050523n. J Med Chem. 2005. PMID: 16335920
Quinic acid derivatives as sialyl Lewis(x)-mimicking selectin inhibitors: design, synthesis, and crystal structure in complex with E-selectin.
Kaila N, Somers WS, Thomas BE, Thakker P, Janz K, DeBernardo S, Tam S, Moore WJ, Yang R, Wrona W, Bedard PW, Crommie D, Keith JC Jr, Tsao DH, Alvarez JC, Ni H, Marchese E, Patton JT, Magnani JL, Camphausen RT. Kaila N, et al. Among authors: somers ws. J Med Chem. 2005 Jun 30;48(13):4346-57. doi: 10.1021/jm050049l. J Med Chem. 2005. PMID: 15974587
18 results