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901 results

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Page 1
LRP8-mediated selenocysteine uptake is a targetable vulnerability in MYCN-amplified neuroblastoma.
Alborzinia H, Chen Z, Yildiz U, Freitas FP, Vogel FCE, Varga JP, Batani J, Bartenhagen C, Schmitz W, Büchel G, Michalke B, Zheng J, Meierjohann S, Girardi E, Espinet E, Flórez AF, Dos Santos AF, Aroua N, Cheytan T, Haenlin J, Schlicker L, Xavier da Silva TN, Przybylla A, Zeisberger P, Superti-Furga G, Eilers M, Conrad M, Fabiano M, Schweizer U, Fischer M, Schulze A, Trumpp A, Friedmann Angeli JP. Alborzinia H, et al. Among authors: schulze a. EMBO Mol Med. 2023 Aug 7;15(8):e18014. doi: 10.15252/emmm.202318014. Epub 2023 Jul 12. EMBO Mol Med. 2023. PMID: 37435859 Free PMC article.
p53 deficient breast cancer cells reprogram preadipocytes toward tumor-protective immunomodulatory cells.
Hassin O, Sernik M, Seligman A, Vogel FCE, Wellenstein MD, Smollich J, Halperin C, Pirona AC, Toledano LN, Caballero CD, Schlicker L, Salame TM, Sarusi Portuguez A, Aylon Y, Scherz-Shouval R, Geiger T, de Visser KE, Schulze A, Oren M. Hassin O, et al. Among authors: schulze a. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2311460120. doi: 10.1073/pnas.2311460120. Epub 2023 Dec 21. Proc Natl Acad Sci U S A. 2023. PMID: 38127986
A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs.
Wang C, Sun M, Shao C, Schlicker L, Zhuo Y, Harim Y, Peng T, Tian W, Stöffler N, Schneider M, Helm D, Chu Y, Fu B, Jin X, Mallm JP, Mall M, Wu Y, Schulze A, Liu HK. Wang C, et al. Among authors: schulze a. NPJ Precis Oncol. 2024 Jan 26;8(1):19. doi: 10.1038/s41698-024-00500-5. NPJ Precis Oncol. 2024. PMID: 38273014 Free PMC article.
Formate promotes invasion and metastasis in reliance on lipid metabolism.
Delbrouck C, Kiweler N, Chen O, Pozdeev VI, Haase L, Neises L, Oudin A, Fouquier d'Hérouël A, Shen R, Schlicker L, Halder R, Lesur A, Schuster A, Lorenz NI, Jaeger C, Feucherolles M, Frache G, Szpakowska M, Chevigne A, Ronellenfitsch MW, Moussay E, Piraud M, Skupin A, Schulze A, Niclou SP, Letellier E, Meiser J. Delbrouck C, et al. Among authors: schulze a. Cell Rep. 2023 Sep 26;42(9):113034. doi: 10.1016/j.celrep.2023.113034. Epub 2023 Aug 30. Cell Rep. 2023. PMID: 37651228 Free article.
Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma.
Sainero-Alcolado L, Garde-Lapido E, Snaebjörnsson MT, Schoch S, Stevens I, Ruiz-Pérez MV, Dyrager C, Pelechano V, Axelson H, Schulze A, Arsenian-Henriksson M. Sainero-Alcolado L, et al. Among authors: schulze a. Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2310479121. doi: 10.1073/pnas.2310479121. Epub 2024 Feb 9. Proc Natl Acad Sci U S A. 2024. PMID: 38335255 Free PMC article.
Palmitate paves the way to lung metastasis.
Winkelkotte AM, Schulze A. Winkelkotte AM, et al. Among authors: schulze a. Trends Cancer. 2023 May;9(5):376-378. doi: 10.1016/j.trecan.2023.03.001. Epub 2023 Mar 21. Trends Cancer. 2023. PMID: 36959035
mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism.
Levy T, Voeltzke K, Hruby L, Alasad K, Bas Z, Snaebjörnsson M, Marciano R, Scharov K, Planque M, Vriens K, Christen S, Funk CM, Hassiepen C, Kahler A, Heider B, Picard D, Lim JKM, Stefanski A, Bendrin K, Vargas-Toscano A, Kahlert UD, Stühler K, Remke M, Elkabets M, Grünewald TGP, Reichert AS, Fendt SM, Schulze A, Reifenberger G, Rotblat B, Leprivier G. Levy T, et al. Among authors: schulze a. Nat Commun. 2024 May 14;15(1):4083. doi: 10.1038/s41467-024-48386-y. Nat Commun. 2024. PMID: 38744825 Free article.
901 results