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Modular Synthesis of Semiconducting Graft Copolymers to Achieve "Clickable" Fluorescent Nanoparticles with Long Circulation and Specific Cancer Targeting.
Creamer A, Fiego AL, Agliano A, Prados-Martin L, Høgset H, Najer A, Richards DA, Wojciechowski JP, Foote JEJ, Kim N, Monahan A, Tang J, Shamsabadi A, Rochet LNC, Thanasi IA, de la Ballina LR, Rapley CL, Turnock S, Love EA, Bugeon L, Dallman MJ, Heeney M, Kramer-Marek G, Chudasama V, Fenaroli F, Stevens MM. Creamer A, et al. Among authors: rochet lnc. Adv Mater. 2023 Mar 11:e2300413. doi: 10.1002/adma.202300413. Online ahead of print. Adv Mater. 2023. PMID: 36905683
Hydrogel Cross-Linking via Thiol-Reactive Pyridazinediones.
Bahou C, Spears RJ, Ramírez Rosales AM, Rochet LNC, Barber LJ, Stankevich KS, Miranda JF, Butcher TC, Kerrigan AM, Lazarov VK, Grey W, Chudasama V, Spicer CD. Bahou C, et al. Among authors: rochet lnc. Biomacromolecules. 2023 Nov 13;24(11):4646-4652. doi: 10.1021/acs.biomac.3c00290. Epub 2023 Oct 4. Biomacromolecules. 2023. PMID: 37792488 Free PMC article.
Rapid Access to Potent Bispecific T Cell Engagers Using Biogenic Tyrosine Click Chemistry.
Shajan I, Rochet LNC, Tracey SR, Jackowska B, Benazza R, Hernandez-Alba O, Cianférani S, Scott CJ, van Delft FL, Chudasama V, Albada B. Shajan I, et al. Among authors: rochet lnc. Bioconjug Chem. 2023 Dec 20;34(12):2215-2220. doi: 10.1021/acs.bioconjchem.3c00357. Epub 2023 Nov 14. Bioconjug Chem. 2023. PMID: 37962868 Free PMC article.
Use of pyridazinediones for tuneable and reversible covalent cysteine modification applied to peptides, proteins and hydrogels.
Rochet LNC, Bahou C, Wojciechowski JP, Koutsopetras I, Britton P, Spears RJ, Thanasi IA, Shao B, Zhong L, Bučar DK, Aliev AE, Porter MJ, Stevens MM, Baker JR, Chudasama V. Rochet LNC, et al. Chem Sci. 2023 Nov 1;14(47):13743-13754. doi: 10.1039/d3sc04976k. eCollection 2023 Dec 6. Chem Sci. 2023. PMID: 38075666 Free PMC article.