Nakazato A - Search Results

1

Scalable synthesis of (+)-2-amino-3-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid as a potent and selective group II metabotropic glutamate receptor agonist.

Sakagami K, Kumagai T, Taguchi T, Nakazato A. Sakagami K, et al. Among authors: nakazato a. Chem Pharm Bull (Tokyo). 2007 Jan;55(1):37-43. doi: 10.1248/cpb.55.37. Chem Pharm Bull (Tokyo). 2007. PMID: 17202699 Free article.

2

MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity.

Chaki S, Yoshikawa R, Hirota S, Shimazaki T, Maeda M, Kawashima N, Yoshimizu T, Yasuhara A, Sakagami K, Okuyama S, Nakanishi S, Nakazato A. Chaki S, et al. Among authors: nakazato a. Neuropharmacology. 2004 Mar;46(4):457-67. doi: 10.1016/j.neuropharm.2003.10.009. Neuropharmacology. 2004. PMID: 14975669

3

Synthesis, in vitro pharmacology, structure-activity relationships, and pharmacokinetics of 3-alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent and selective group II metabotropic glutamate receptor antagonists.

Nakazato A, Sakagami K, Yasuhara A, Ohta H, Yoshikawa R, Itoh M, Nakamura M, Chaki S. Nakazato A, et al. J Med Chem. 2004 Aug 26;47(18):4570-87. doi: 10.1021/jm0400294. J Med Chem. 2004. PMID: 15317467

4

In vitro and in vivo evaluation of the metabolism and bioavailability of ester prodrugs of mgs0039 (3-(3,4-dichlorobenzyloxy)-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid), a potent metabotropic glutamate receptor antagonist.

Nakamura M, Kawakita Y, Yasuhara A, Fukasawa Y, Yoshida K, Sakagami K, Nakazato A. Nakamura M, et al. Among authors: nakazato a. Drug Metab Dispos. 2006 Mar;34(3):369-74. doi: 10.1124/dmd.105.006213. Epub 2005 Dec 2. Drug Metab Dispos. 2006. PMID: 16326817

5

Prodrugs of 3-(3,4-dichlorobenzyloxy)-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (MGS0039): a potent and orally active group II mGluR antagonist with antidepressant-like potential.

Yasuhara A, Nakamura M, Sakagami K, Shimazaki T, Yoshikawa R, Chaki S, Ohta H, Nakazato A. Yasuhara A, et al. Among authors: nakazato a. Bioorg Med Chem. 2006 Jun 15;14(12):4193-207. doi: 10.1016/j.bmc.2006.01.060. Epub 2006 Feb 17. Bioorg Med Chem. 2006. PMID: 16487713

6

Synthesis, in vitro pharmacology, and structure-activity relationships of 2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as mGluR2 antagonists.

Yasuhara A, Sakagami K, Yoshikawa R, Chaki S, Nakamura M, Nakazato A. Yasuhara A, et al. Among authors: nakazato a. Bioorg Med Chem. 2006 May 15;14(10):3405-20. doi: 10.1016/j.bmc.2005.12.061. Epub 2006 Jan 20. Bioorg Med Chem. 2006. PMID: 16431115

7

Synthesis, in vitro pharmacology, and pharmacokinetic profiles of 2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-1-fluorocyclopropanecarboxylic acid and its 6-heptyl ester, a potent mGluR2 antagonist.

Sakagami K, Yasuhara A, Chaki S, Yoshikawa R, Kawakita Y, Saito A, Taguchi T, Nakazato A. Sakagami K, et al. Among authors: nakazato a. Bioorg Med Chem. 2008 Apr 15;16(8):4359-66. doi: 10.1016/j.bmc.2008.02.066. Epub 2008 Feb 26. Bioorg Med Chem. 2008. PMID: 18348906

8

In vitro and in vivo pharmacological profile of 5-[2-[4-(6-fluoro-1H-indole-3-yl)piperidin-1-yl]ethyl]-4-(4-fluorophenyl)thiazole-2-carboxylic acid amide (NRA0562), a novel and putative atypical antipsychotic.

Funakoshi T, Chaki S, Kawashima N, Suzuki Y, Yoshikawa R, Kumagai T, Nakazato A, Kameo K, Goto M, Okuyama S. Funakoshi T, et al. Among authors: nakazato a. Life Sci. 2002 Aug 9;71(12):1371-84. doi: 10.1016/s0024-3205(02)01863-5. Life Sci. 2002. PMID: 12127158

9

Identification of arginine analogues as antagonists and agonists for the melanocortin-4 receptor.

Nozawa D, Okubo T, Chaki S, Okuyama S, Nakazato A. Nozawa D, et al. Among authors: nakazato a. Chem Pharm Bull (Tokyo). 2007 Aug;55(8):1232-9. doi: 10.1248/cpb.55.1232. Chem Pharm Bull (Tokyo). 2007. PMID: 17666851 Free article.

10

Synthesis of diphenylmethyl analogues and their affinity for the melanocortin-4 receptor and the serotonin transporter.

Nozawa D, Okubo T, Ishii T, Chaki S, Okuyama S, Nakazato A. Nozawa D, et al. Among authors: nakazato a. Chem Pharm Bull (Tokyo). 2007 Jul;55(7):1044-50. doi: 10.1248/cpb.55.1044. Chem Pharm Bull (Tokyo). 2007. PMID: 17603198 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

93 results

Search Page