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The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells.
Sabater L, Nicolau-Travers ML, De Rache A, Prado E, Dejeu J, Bombarde O, Lacroix J, Calsou P, Defrancq E, Mergny JL, Gomez D, Pratviel G. Sabater L, et al. Among authors: mergny jl. J Biol Inorg Chem. 2015 Jun;20(4):729-38. doi: 10.1007/s00775-015-1260-8. Epub 2015 Apr 7. J Biol Inorg Chem. 2015. PMID: 25846142
Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration.
Gomez D, Aouali N, Londoño-Vallejo A, Lacroix L, Mégnin-Chanet F, Lemarteleur T, Douarre C, Shin-ya K, Mailliet P, Trentesaux C, Morjani H, Mergny JL, Riou JF. Gomez D, et al. Among authors: mergny jl. J Biol Chem. 2003 Dec 12;278(50):50554-62. doi: 10.1074/jbc.M308440200. Epub 2003 Oct 2. J Biol Chem. 2003. PMID: 14525974 Free article.
Interaction of telomestatin with the telomeric single-strand overhang.
Gomez D, Paterski R, Lemarteleur T, Shin-Ya K, Mergny JL, Riou JF. Gomez D, et al. Among authors: mergny jl. J Biol Chem. 2004 Oct 1;279(40):41487-94. doi: 10.1074/jbc.M406123200. Epub 2004 Jul 23. J Biol Chem. 2004. PMID: 15277522 Free article.
Preferential binding of a G-quadruplex ligand to human chromosome ends.
Granotier C, Pennarun G, Riou L, Hoffschir F, Gauthier LR, De Cian A, Gomez D, Mandine E, Riou JF, Mergny JL, Mailliet P, Dutrillaux B, Boussin FD. Granotier C, et al. Among authors: mergny jl. Nucleic Acids Res. 2005 Jul 28;33(13):4182-90. doi: 10.1093/nar/gki722. Print 2005. Nucleic Acids Res. 2005. PMID: 16052031 Free PMC article.
Nucleic acids targeted to drugs: SELEX against a quadruplex ligand.
Renaud de la Faverie A, Hamon F, Di Primo C, Largy E, Dausse E, Delaurière L, Landras-Guetta C, Toulmé JJ, Teulade-Fichou MP, Mergny JL. Renaud de la Faverie A, et al. Among authors: mergny jl. Biochimie. 2011 Aug;93(8):1357-67. doi: 10.1016/j.biochi.2011.05.022. Epub 2011 May 31. Biochimie. 2011. PMID: 21664224
308 results