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A novel crystallization-induced diastereomeric transformation based on a reversible carbon-sulfur bond formation. Application to the synthesis of a gamma-secretase inhibitor.
Davies AJ, Scott JP, Bishop BC, Brands KM, Brewer SE, Dasilva JO, Dormer PG, Dolling UH, Gibb AD, Hammond DC, Lieberman DR, Palucki M, Payack JF. Davies AJ, et al. Among authors: lieberman dr. J Org Chem. 2007 Jun 22;72(13):4864-71. doi: 10.1021/jo0705925. Epub 2007 May 24. J Org Chem. 2007. PMID: 17521199
A practical synthesis of a gamma-secretase inhibitor.
Scott JP, Lieberman DR, Beureux OM, Brands KM, Davies AJ, Gibson AW, Hammond DC, McWilliams CJ, Stewart GW, Wilson RD, Dolling UH. Scott JP, et al. Among authors: lieberman dr. J Org Chem. 2007 May 25;72(11):4149-55. doi: 10.1021/jo070407n. Epub 2007 Apr 28. J Org Chem. 2007. PMID: 17465573
953 results