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Structure-activity relationships of truncated C2- or C8-substituted adenosine derivatives as dual acting A₂A and A₃ adenosine receptor ligands.
Hou X, Majik MS, Kim K, Pyee Y, Lee Y, Alexander V, Chung HJ, Lee HW, Chandra G, Lee JH, Park SG, Choi WJ, Kim HO, Phan K, Gao ZG, Jacobson KA, Choi S, Lee SK, Jeong LS. Hou X, et al. Among authors: lee y, lee sk, lee hw, lee jh. J Med Chem. 2012 Jan 12;55(1):342-56. doi: 10.1021/jm201229j. Epub 2011 Dec 28. J Med Chem. 2012. PMID: 22142423 Free PMC article.
Discovery of a new nucleoside template for human A3 adenosine receptor ligands: D-4'-thioadenosine derivatives without 4'-hydroxymethyl group as highly potent and selective antagonists.
Jeong LS, Choe SA, Gunaga P, Kim HO, Lee HW, Lee SK, Tosh DK, Patel A, Palaniappan KK, Gao ZG, Jacobson KA, Moon HR. Jeong LS, et al. Among authors: lee sk, lee hw. J Med Chem. 2007 Jul 12;50(14):3159-62. doi: 10.1021/jm070259t. Epub 2007 Jun 8. J Med Chem. 2007. PMID: 17555308
Stereoselective synthesis of 1'-functionalized-4'-thionucleosides.
Jeong LS, Gunaga P, Kim HO, Tosh DK, Lee HW, Choe SA, Moon HR, Gao ZG, Jacobson KA, Chun MW. Jeong LS, et al. Among authors: lee hw. Nucleosides Nucleotides Nucleic Acids. 2007;26(8-9):1011-4. doi: 10.1080/15257770701508588. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18058527 Free PMC article.
3,502 results