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Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids.
Kysilov B, Kuchtiak V, Hrcka Krausova B, Balik A, Korinek M, Fili K, Dobrovolski M, Abramova V, Chodounska H, Kudova E, Bozikova P, Cerny J, Smejkalova T, Vyklicky L. Kysilov B, et al. Among authors: korinek m. Cell Mol Life Sci. 2024 Jan 12;81(1):36. doi: 10.1007/s00018-023-05062-6. Cell Mol Life Sci. 2024. PMID: 38214768 Free PMC article.
Effects of Pregnanolone Glutamate and Its Metabolites on GABAA and NMDA Receptors and Zebrafish Behavior.
Abramova V, Leal Alvarado V, Hill M, Smejkalova T, Maly M, Vales K, Dittert I, Bozikova P, Kysilov B, Hrcka Krausova B, Vyklicky V, Balik A, Fili K, Korinek M, Chodounska H, Kudova E, Ciz D, Martinovic J, Cerny J, Bartunek P, Vyklicky L. Abramova V, et al. Among authors: korinek m. ACS Chem Neurosci. 2023 May 17;14(10):1870-1883. doi: 10.1021/acschemneuro.3c00131. Epub 2023 May 1. ACS Chem Neurosci. 2023. PMID: 37126803 Free PMC article.
Anti-viral and Anti-inflammatory Isoflavonoids from Ukrainian Iris aphylla Rhizomes: Structure-Activity Relationship Coupled with ChemGPS-NP Analysis.
Mykhailenko O, Hsieh CF, El-Shazly M, Nikishin A, Kovalyov V, Shynkarenko P, Ivanauskas L, Chen BH, Horng JT, Hwang TL, Georgiyants V, Korinek M. Mykhailenko O, et al. Among authors: korinek m. Planta Med. 2023 Sep;89(11):1063-1073. doi: 10.1055/a-2063-5265. Epub 2023 Mar 28. Planta Med. 2023. PMID: 36977489
Agent-based models of human response to natural hazards: systematic review of tsunami evacuation.
Mls K, Kořínek M, Štekerová K, Tučník P, Bureš V, Čech P, Husáková M, Mikulecký P, Nacházel T, Ponce D, Zanker M, Babič F, Triantafyllou I. Mls K, et al. Among authors: korinek m. Nat Hazards (Dordr). 2023;115(3):1887-1908. doi: 10.1007/s11069-022-05643-x. Epub 2022 Oct 5. Nat Hazards (Dordr). 2023. PMID: 36212893 Free PMC article. Review.
Comparative LC-LTQ-MS-MS Analysis of the Leaf Extracts of Lantana camara and Lantana montevidensis Growing in Egypt with Insights into Their Antioxidant, Anti-Inflammatory, and Cytotoxic Activities.
El-Din MIG, Fahmy NM, Wu F, Salem MM, Khattab OM, El-Seedi HR, Korinek M, Hwang TL, Osman AK, El-Shazly M, Fayez S. El-Din MIG, et al. Among authors: korinek m. Plants (Basel). 2022 Jun 27;11(13):1699. doi: 10.3390/plants11131699. Plants (Basel). 2022. PMID: 35807651 Free PMC article.
Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations.
Kysilov B, Hrcka Krausova B, Vyklicky V, Smejkalova T, Korinek M, Horak M, Chodounska H, Kudova E, Cerny J, Vyklicky L. Kysilov B, et al. Among authors: korinek m. Br J Pharmacol. 2022 Aug;179(15):3970-3990. doi: 10.1111/bph.15841. Epub 2022 Apr 8. Br J Pharmacol. 2022. PMID: 35318645 Free article.
Pharmacological Potential and Chemical Composition of Crocus sativus Leaf Extracts.
Mykhailenko O, Petrikaite V, Korinek M, Chang FR, El-Shazly M, Yen CH, Bezruk I, Chen BH, Hsieh CF, Lytkin D, Ivanauskas L, Georgiyants V, Hwang TL. Mykhailenko O, et al. Among authors: korinek m. Molecules. 2021 Dec 21;27(1):10. doi: 10.3390/molecules27010010. Molecules. 2021. PMID: 35011243 Free PMC article.
68 results