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Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
Golebiewska A, Hau AC, Oudin A, Stieber D, Yabo YA, Baus V, Barthelemy V, Klein E, Bougnaud S, Keunen O, Wantz M, Michelucci A, Neirinckx V, Muller A, Kaoma T, Nazarov PV, Azuaje F, De Falco A, Flies B, Richart L, Poovathingal S, Arns T, Grzyb K, Mock A, Herold-Mende C, Steino A, Brown D, May P, Miletic H, Malta TM, Noushmehr H, Kwon YJ, Jahn W, Klink B, Tanner G, Stead LF, Mittelbronn M, Skupin A, Hertel F, Bjerkvig R, Niclou SP. Golebiewska A, et al. Among authors: klein e. Acta Neuropathol. 2020 Dec;140(6):919-949. doi: 10.1007/s00401-020-02226-7. Epub 2020 Oct 3. Acta Neuropathol. 2020. PMID: 33009951 Free PMC article.
The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein-protein interaction in glioblastoma.
Neirinckx V, Hau AC, Schuster A, Fritah S, Tiemann K, Klein E, Nazarov PV, Matagne A, Szpakowska M, Meyrath M, Chevigné A, Schmidt MHH, Niclou SP. Neirinckx V, et al. Among authors: klein e. Neurooncol Adv. 2019 Sep 6;1(1):vdz024. doi: 10.1093/noajnl/vdz024. eCollection 2019 May-Dec. Neurooncol Adv. 2019. PMID: 32642659 Free PMC article.
AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion.
Schuster A, Klein E, Neirinckx V, Knudsen AM, Fabian C, Hau AC, Dieterle M, Oudin A, Nazarov PV, Golebiewska A, Muller A, Perez-Hernandez D, Rodius S, Dittmar G, Bjerkvig R, Herold-Mende C, Klink B, Kristensen BW, Niclou SP. Schuster A, et al. Among authors: klein e. Nat Commun. 2020 Dec 11;11(1):6366. doi: 10.1038/s41467-020-20029-y. Nat Commun. 2020. PMID: 33311477 Free PMC article.
Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors.
Oudin A, Baus V, Barthelemy V, Fabian C, Klein E, Dieterle M, Wantz M, Hau AC, Dording C, Bernard A, Michelucci A, Yabo YA, Kanli G, Keunen O, Bjerkvig R, Niclou SP, Golebiewska A. Oudin A, et al. Among authors: klein e. STAR Protoc. 2021 May 12;2(2):100534. doi: 10.1016/j.xpro.2021.100534. eCollection 2021 Jun 18. STAR Protoc. 2021. PMID: 34027491 Free PMC article.
IL1R1+ cancer-associated fibroblasts drive tumor development and immunosuppression in colorectal cancer.
Koncina E, Nurmik M, Pozdeev VI, Gilson C, Tsenkova M, Begaj R, Stang S, Gaigneaux A, Weindorfer C, Rodriguez F, Schmoetten M, Klein E, Karta J, Atanasova VS, Grzyb K, Ullmann P, Halder R, Hengstschläger M, Graas J, Augendre V, Karapetyan YE, Kerger L, Zuegel N, Skupin A, Haan S, Meiser J, Dolznig H, Letellier E. Koncina E, et al. Among authors: klein e. Nat Commun. 2023 Jul 17;14(1):4251. doi: 10.1038/s41467-023-39953-w. Nat Commun. 2023. PMID: 37460545 Free PMC article.
Accuracy of Influenza ICD-10 Diagnosis Codes in Identifying Influenza Illness in Children.
Antoon JW, Stopczynski T, Amarin JZ, Stewart LS, Boom JA, Sahni LC, Michaels MG, Williams JV, Englund JA, Klein EJ, Staat MA, Schlaudecker EP, Selvarangan R, Schuster JE, Weinberg GA, Szilagyi PG, Perez A, Moline HL, Spieker AJ, Grijalva CG, Olson SM, Halasa NB. Antoon JW, et al. Among authors: klein ej. JAMA Netw Open. 2024 Apr 1;7(4):e248255. doi: 10.1001/jamanetworkopen.2024.8255. JAMA Netw Open. 2024. PMID: 38656577 Free PMC article.
3,447 results