Hideg K - Search Results

1

Synthesis of Spin-Labelled Bergamottin: A Potent CYP3A4 Inhibitor with Antiproliferative Activity.

Zsidó BZ, Balog M, Erős N, Poór M, Mohos V, Fliszár-Nyúl E, Hetényi C, Nagane M, Hideg K, Kálai T, Bognár B. Zsidó BZ, et al. Among authors: hideg k. Int J Mol Sci. 2020 Jan 13;21(2):508. doi: 10.3390/ijms21020508. Int J Mol Sci. 2020. PMID: 31941150 Free PMC article.

2

Synthesis and study of 2-amino-7-bromofluorenes modified with nitroxides and their precursors as dual anti-amyloid and antioxidant active compounds.

Kálai T, Petrlova J, Balog M, Aung HH, Voss JC, Hideg K. Kálai T, et al. Among authors: hideg k. Eur J Med Chem. 2011 Apr;46(4):1348-55. doi: 10.1016/j.ejmech.2011.01.059. Epub 2011 Feb 3. Eur J Med Chem. 2011. PMID: 21333407 Free PMC article.

3

Synthesis of N-substituted 3,5-bis(arylidene)-4-piperidones with high antitumor and antioxidant activity.

Kálai T, Kuppusamy ML, Balog M, Selvendiran K, Rivera BK, Kuppusamy P, Hideg K. Kálai T, et al. Among authors: hideg k. J Med Chem. 2011 Aug 11;54(15):5414-21. doi: 10.1021/jm200353f. Epub 2011 Jul 6. J Med Chem. 2011. PMID: 21702507

The results showed that all DAP compounds induced a significant loss of cell viability in the human cancer cell lines tested; however, only pyrroline appended nitroxides (5c (Selvendiran, K.; Tong, L.; Bratasz, A.; Kuppusamy, L. M.; Ahmed, S.; Ravi, Y.; Trigg, N. J.; River …

The results showed that all DAP compounds induced a significant loss of cell viability in the human cancer cell lines tested; however, only …

4

Synthesis and Biological Evaluation of Curcumin-Nitroxide-Based Molecular Hybrids as Antioxidant and Anti-Proliferative Agents.

Bognar B, Kuppusamy ML, Madan E, Kalai T, Balog M, Jeko J, Kuppusamy P, Hideg K. Bognar B, et al. Among authors: hideg k. Med Chem. 2017;13(8):761-772. doi: 10.2174/1871520617666170522124712. Med Chem. 2017. PMID: 28530545

5

Antiproliferative Effect of a Novel 4,4'-Disulfonyldiarylidenyl Piperidone in Human Colon Cancer Cells.

Prabhat AM, Kuppusamy ML, Bognár B, Kálai T, Hideg K, Kuppusamy P. Prabhat AM, et al. Among authors: hideg k. Cell Biochem Biophys. 2019 Mar;77(1):61-67. doi: 10.1007/s12013-018-0862-5. Epub 2018 Dec 14. Cell Biochem Biophys. 2019. PMID: 30552554

6

Synthesis and evaluation of the permeability transition inhibitory characteristics of paramagnetic and diamagnetic amiodarone derivatives.

Kálai T, Várbiró G, Bognár Z, Pálfi A, Hantó K, Bognár B, Osz E, Sümegi B, Hideg K. Kálai T, et al. Among authors: hideg k. Bioorg Med Chem. 2005 Apr 1;13(7):2629-36. doi: 10.1016/j.bmc.2005.01.028. Bioorg Med Chem. 2005. PMID: 15755662

7

Structure-activity studies on the protection of Trimetazidine derivatives modified with nitroxides and their precursors from myocardial ischemia-reperfusion injury.

Kálai T, Khan M, Balog M, Kutala VK, Kuppusamy P, Hideg K. Kálai T, et al. Among authors: hideg k. Bioorg Med Chem. 2006 Aug 15;14(16):5510-6. doi: 10.1016/j.bmc.2006.04.040. Epub 2006 May 12. Bioorg Med Chem. 2006. PMID: 16697647

8

Novel antioxidants in anthracycline cardiotoxicity.

Hideg K, Kálai T. Hideg K, et al. Cardiovasc Toxicol. 2007;7(2):160-4. doi: 10.1007/s12012-007-0019-z. Cardiovasc Toxicol. 2007. PMID: 17652823 Review.

9

New poly(ADP-ribose) polymerase-1 inhibitors with antioxidant activity based on 4-carboxamidobenzimidazole-2-ylpyrroline and -tetrahydropyridine nitroxides and their precursors.

Kálai T, Balog M, Szabó A, Gulyás G, Jeko J, Sümegi B, Hideg K. Kálai T, et al. Among authors: hideg k. J Med Chem. 2009 Mar 26;52(6):1619-29. doi: 10.1021/jm801476y. J Med Chem. 2009. PMID: 19245212

10

Synthesis and study of new paramagnetic and diamagnetic verapamil derivatives.

Bognár B, Ahmed S, Kuppusamy ML, Selvendiran K, Khan M, Jeko J, Hankovszky OH, Kálai T, Kuppusamy P, Hideg K. Bognár B, et al. Among authors: hideg k. Bioorg Med Chem. 2010 Apr 15;18(8):2954-63. doi: 10.1016/j.bmc.2010.02.040. Epub 2010 Feb 25. Bioorg Med Chem. 2010. PMID: 20347319 Free PMC article.

The basic structure was modified by changing the nitrile group to an amide or the methyl substituent on tertiary nitrogen with nitroxides and their reduced forms (hydroxylamine and secondary amines). Among the new verapamil derivatives compound 16B [Mohan, I. K.; Kahn, M.; …

The basic structure was modified by changing the nitrile group to an amide or the methyl substituent on tertiary nitrogen with nitroxides an …

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