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Islet amyloid polypeptide inserts into phospholipid monolayers as monomer.
Engel MF, Yigittop H, Elgersma RC, Rijkers DT, Liskamp RM, de Kruijff B, Höppener JW, Antoinette Killian J. Engel MF, et al. Among authors: hoppener jw. J Mol Biol. 2006 Feb 24;356(3):783-9. doi: 10.1016/j.jmb.2005.12.020. Epub 2005 Dec 21. J Mol Biol. 2006. PMID: 16403520
Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane.
Engel MF, Khemtémourian L, Kleijer CC, Meeldijk HJ, Jacobs J, Verkleij AJ, de Kruijff B, Killian JA, Höppener JW. Engel MF, et al. Among authors: hoppener jw. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6033-8. doi: 10.1073/pnas.0708354105. Epub 2008 Apr 11. Proc Natl Acad Sci U S A. 2008. PMID: 18408164 Free PMC article.
The N-terminal fragment of human islet amyloid polypeptide is non-fibrillogenic in the presence of membranes and does not cause leakage of bilayers of physiologically relevant lipid composition.
Khemtémourian L, Engel MF, Liskamp RM, Höppener JW, Killian JA. Khemtémourian L, et al. Among authors: hoppener jw. Biochim Biophys Acta. 2010 Sep;1798(9):1805-11. doi: 10.1016/j.bbamem.2010.05.022. Epub 2010 Jun 4. Biochim Biophys Acta. 2010. PMID: 20570648 Free article.
108 results