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Derivatives of imidazotriazine and pyrrolotriazine C-nucleosides as potential new anti-HCV agents.
Draffan AG, Frey B, Fraser BH, Pool B, Gannon C, Tyndall EM, Cianci J, Harding M, Lilly M, Hufton R, Halim R, Jahangiri S, Bond S, Jeynes TP, Nguyen VT, Wirth V, Luttick A, Tilmanis D, Pryor M, Porter K, Morton CJ, Lin B, Duan J, Bethell RC, Kukolj G, Simoneau B, Tucker SP. Draffan AG, et al. Among authors: fraser bh. Bioorg Med Chem Lett. 2014 Nov 1;24(21):4984-8. doi: 10.1016/j.bmcl.2014.09.030. Epub 2014 Sep 21. Bioorg Med Chem Lett. 2014. PMID: 25288185
Evaluation of the antidepressant therapeutic potential of isocyanine and pseudoisocyanine analogues of the organic cation decynium-22.
Krause-Heuer AM, Fraser-Spears R, Dobrowolski JC, Ashford ME, Wyatt NA, Roberts MP, Gould GG, Cheah WC, Ng CKL, Bhadbhade M, Zhang B, Greguric I, Wheate NJ, Kumar N, Koek W, Callaghan PD, Daws LC, Fraser BH. Krause-Heuer AM, et al. Among authors: fraser spears r, fraser bh. Eur J Med Chem. 2017 Sep 8;137:476-487. doi: 10.1016/j.ejmech.2017.06.011. Epub 2017 Jun 7. Eur J Med Chem. 2017. PMID: 28624702 Free PMC article.
Synthesis and in Vivo Evaluation of [123I]Melanin-Targeted Agents.
Roberts MP, Nguyen V, Ashford ME, Berghofer P, Wyatt NA, Krause-Heuer AM, Pham TQ, Taylor SR, Hogan L, Jiang CD, Fraser BH, Lengkeek NA, Matesic L, Gregoire MC, Denoyer D, Hicks RJ, Katsifis A, Greguric I. Roberts MP, et al. Among authors: fraser bh. J Med Chem. 2015 Aug 13;58(15):6214-24. doi: 10.1021/acs.jmedchem.5b00777. Epub 2015 Jul 29. J Med Chem. 2015. PMID: 26177000
Comparative analysis of novel decynium-22 analogs to inhibit transport by the low-affinity, high-capacity monoamine transporters, organic cation transporters 2 and 3, and plasma membrane monoamine transporter.
Fraser-Spears R, Krause-Heuer AM, Basiouny M, Mayer FP, Manishimwe R, Wyatt NA, Dobrowolski JC, Roberts MP, Greguric I, Kumar N, Koek W, Sitte HH, Callaghan PD, Fraser BH, Daws LC. Fraser-Spears R, et al. Among authors: fraser bh. Eur J Pharmacol. 2019 Jan 5;842:351-364. doi: 10.1016/j.ejphar.2018.10.028. Epub 2018 Oct 25. Eur J Pharmacol. 2019. PMID: 30473490 Free PMC article.
Fluorescence-activated cell sorting to reveal the cell origin of radioligand binding.
Tournier BB, Tsartsalis S, Ceyzériat K, Medina Z, Fraser BH, Grégoire MC, Kövari E, Millet P. Tournier BB, et al. Among authors: fraser bh. J Cereb Blood Flow Metab. 2020 Jun;40(6):1242-1255. doi: 10.1177/0271678X19860408. Epub 2019 Jun 26. J Cereb Blood Flow Metab. 2020. PMID: 31242048 Free PMC article.
Synthesis, bioconjugation and stability studies of [18 F]ethenesulfonyl fluoride.
Zhang B, Pascali G, Wyatt N, Matesic L, Klenner MA, Sia TR, Guastella AJ, Massi M, Robinson AJ, Fraser BH. Zhang B, et al. Among authors: fraser bh. J Labelled Comp Radiopharm. 2018 Sep;61(11):847-856. doi: 10.1002/jlcr.3667. Epub 2018 Jul 12. J Labelled Comp Radiopharm. 2018. PMID: 29924425
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