El Marrouni A - Search Results

1

Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1.

Balibar CJ, Klein DJ, Zamlynny B, Diamond TL, Fang Z, Cheney CA, Kristoff J, Lu M, Bukhtiyarova M, Ou Y, Xu M, Ba L, Carroll SS, El Marrouni A, Fay JF, Forster A, Goh SL, Gu M, Krosky D, Rosenbloom DIS, Sheth P, Wang D, Wu G, Zebisch M, Zhao T, Zuck P, Grobler J, Hazuda DJ, Howell BJ, Converso A. Balibar CJ, et al. Among authors: el marrouni a. Sci Transl Med. 2023 Feb 22;15(684):eabn2038. doi: 10.1126/scitranslmed.abn2038. Epub 2023 Feb 22. Sci Transl Med. 2023. PMID: 36812345

2

Synthesis of new unnatural N(α)-Fmoc pyrimidin-4-one amino acids: use of the p-benzyloxybenzyloxy group as a pyrimidinone masking group.

ElMarrouni A, Heras M. ElMarrouni A, et al. Org Biomol Chem. 2015 Jan 21;13(3):851-8. doi: 10.1039/c4ob02235a. Org Biomol Chem. 2015. PMID: 25407750

3

Synthesis of C6-Substituted Purine Nucleoside Analogues via Late-Stage Photoredox/Nickel Dual Catalytic Cross-Coupling.

Perkins JJ, Shurtleff VW, Johnson AM, El Marrouni A. Perkins JJ, et al. Among authors: el marrouni a. ACS Med Chem Lett. 2021 Mar 8;12(4):662-666. doi: 10.1021/acsmedchemlett.0c00673. eCollection 2021 Apr 8. ACS Med Chem Lett. 2021. PMID: 33859805 Free PMC article.

4

Development of a sp²-sp³ Stille Cross-Coupling for Rapid Synthesis of HIV NNRTI Doravirine Analogues.

ElMarrouni A, Campbell M, Perkins JJ, Converso A. ElMarrouni A, et al. Org Lett. 2017 Jun 16;19(12):3071-3074. doi: 10.1021/acs.orglett.7b01142. Epub 2017 Jun 7. Org Lett. 2017. PMID: 28589720

5

Dose Number as a Tool to Guide Lead Optimization for Orally Bioavailable Compounds in Drug Discovery.

Wuelfing WP, El Marrouni A, Lipert MP, Daublain P, Kesisoglou F, Converso A, Templeton AC. Wuelfing WP, et al. Among authors: el marrouni a. J Med Chem. 2022 Feb 10;65(3):1685-1694. doi: 10.1021/acs.jmedchem.1c01687. Epub 2022 Jan 21. J Med Chem. 2022. PMID: 35060378

6

Metal-Free Addition of Alkyl Bromides to Access 3,3-Disubstituted Quinoxalinones Enabled by Visible-Light Photoredox Catalysis.

Liao J, Hunter DN, Oloyede UN, McLaughlin JW, Wang C, El Marrouni A. Liao J, et al. Among authors: el marrouni a. J Org Chem. 2023 Aug 18;88(16):11762-11766. doi: 10.1021/acs.joc.3c01054. Epub 2023 Aug 9. J Org Chem. 2023. PMID: 37556226

7

Silyl-mediated photoredox-catalyzed Giese reaction: addition of non-activated alkyl bromides.

ElMarrouni A, Ritts CB, Balsells J. ElMarrouni A, et al. Chem Sci. 2018 Jul 11;9(32):6639-6646. doi: 10.1039/c8sc02253d. eCollection 2018 Aug 28. Chem Sci. 2018. PMID: 30310596 Free PMC article.

8

High-Throughput Photo- and Electrochemical sp²-sp³ Cross-Electrophile Coupling to Access Novel Tedizolid Analogs.

Montero Bastidas JR, L'Heureux S, Liu W, Lee K, El Marrouni A. Montero Bastidas JR, et al. Among authors: el marrouni a. ACS Med Chem Lett. 2023 May 1;14(5):666-671. doi: 10.1021/acsmedchemlett.2c00542. eCollection 2023 May 11. ACS Med Chem Lett. 2023. PMID: 37197470

9

Activity of Tricyclic Pyrrolopyrimidine Gyrase B Inhibitor against Mycobacterium abscessus.

Madani A, Negatu DA, El Marrouni A, Miller RR, Boyce CW, Murgolo N, Bungard CJ, Zimmerman MD, Dartois V, Gengenbacher M, Olsen DB, Dick T. Madani A, et al. Among authors: el marrouni a. Antimicrob Agents Chemother. 2022 Sep 20;66(9):e0066922. doi: 10.1128/aac.00669-22. Epub 2022 Aug 25. Antimicrob Agents Chemother. 2022. PMID: 36005813 Free PMC article.

10

Total Synthesis of Putative 11-epi-Lyngbouilloside Aglycon.

Kolleth A, Gebauer J, ElMarrouni A, Lebeuf R, Prévost C, Brohan E, Arseniyadis S, Cossy J. Kolleth A, et al. Front Chem. 2016 Aug 9;4:34. doi: 10.3389/fchem.2016.00034. eCollection 2016. Front Chem. 2016. PMID: 27556024 Free PMC article.

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