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An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells.
Girard RM, Crispim M, Stolić I, Damasceno FS, Santos da Silva M, Pral EM, Elias MC, Bajić M, Silber AM. Girard RM, et al. Among authors: damasceno fs. Antimicrob Agents Chemother. 2016 Sep 23;60(10):5867-77. doi: 10.1128/AAC.01595-15. Print 2016 Oct. Antimicrob Agents Chemother. 2016. PMID: 27431229 Free PMC article.
The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host-cell infection.
Crispim M, Damasceno FS, Hernández A, Barisón MJ, Pretto Sauter I, Souza Pavani R, Santos Moura A, Pral EMF, Cortez M, Elias MC, Silber AM. Crispim M, et al. Among authors: damasceno fs. PLoS Negl Trop Dis. 2018 Jan 10;12(1):e0006170. doi: 10.1371/journal.pntd.0006170. eCollection 2018 Jan. PLoS Negl Trop Dis. 2018. PMID: 29320490 Free PMC article.
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