Seropositivity for Chagas disease in blood donors from the state of Alagoas, Northeastern Brazil: an 11-year time series study

Rev Soc Bras Med Trop. 2021 Dec 17:54:e03392021. doi: 10.1590/0037-8682-0339-2021. eCollection 2021.

Abstract

Introduction: Chagas disease can be transmitted by blood transfusion. Herein, we assessed the seropositivity for Chagas disease in blood donors from Alagoas, during 2010-2020.

Methods: Data were requested from the Alagoas blood center. Time trend analysis was performed using a joinpoint regression model.

Results: Seropositivity rate during the study period was 0.35%, which decreased from 2014 to 2020, (annual percentage change, APC = -29.38; p-value <0.05), while the total number of tests performed remained stable (APC = 6.5).

Conclusions: Despite the drop in the seropositivity for Chagas infection in donors, it is imperative to maintain the screening of donors for the epidemiological control.

MeSH terms

  • Blood Donors*
  • Brazil / epidemiology
  • Chagas Disease* / epidemiology
  • Humans
  • Mass Screening
  • Time Factors