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The NR4A agonist, Cytosporone B, attenuates pro-inflammatory mediators in human colorectal cancer tissue ex vivo.
Ismaiel M, Murphy B, Aldhafiri S, Giffney HE, Thornton K, Mukhopadhya A, Keogh CE, Fattah S, Mohan HM, Cummins EP, Murphy EP, Winter DC, Crean D. Ismaiel M, et al. Among authors: cummins ep. Biochem Biophys Res Commun. 2021 May 21;554:179-185. doi: 10.1016/j.bbrc.2021.03.110. Epub 2021 Mar 30. Biochem Biophys Res Commun. 2021. PMID: 33798945 Free article.
The role of HIF in immunity and inflammation.
Cummins EP, Keogh CE, Crean D, Taylor CT. Cummins EP, et al. Mol Aspects Med. 2016 Feb-Mar;47-48:24-34. doi: 10.1016/j.mam.2015.12.004. Epub 2016 Jan 6. Mol Aspects Med. 2016. PMID: 26768963 Review.
REST is a hypoxia-responsive transcriptional repressor.
Cavadas MA, Mesnieres M, Crifo B, Manresa MC, Selfridge AC, Keogh CE, Fabian Z, Scholz CC, Nolan KA, Rocha LM, Tambuwala MM, Brown S, Wdowicz A, Corbett D, Murphy KJ, Godson C, Cummins EP, Taylor CT, Cheong A. Cavadas MA, et al. Among authors: cummins ep. Sci Rep. 2016 Aug 17;6:31355. doi: 10.1038/srep31355. Sci Rep. 2016. PMID: 27531581 Free PMC article.
Hypoxia and inflammatory bowel disease.
Cummins EP, Crean D. Cummins EP, et al. Microbes Infect. 2017 Mar;19(3):210-221. doi: 10.1016/j.micinf.2016.09.004. Epub 2016 Sep 20. Microbes Infect. 2017. PMID: 27664046 Free article. Review.
Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-β1 signaling. [corrected].
Manresa MC, Tambuwala MM, Radhakrishnan P, Harnoss JM, Brown E, Cavadas MA, Keogh CE, Cheong A, Barrett KE, Cummins EP, Schneider M, Taylor CT. Manresa MC, et al. Among authors: cummins ep. Am J Physiol Gastrointest Liver Physiol. 2016 Dec 1;311(6):G1076-G1090. doi: 10.1152/ajpgi.00229.2016. Epub 2016 Oct 27. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27789456 Free article.
NR4A Receptors Differentially Regulate NF-κB Signaling in Myeloid Cells.
McEvoy C, de Gaetano M, Giffney HE, Bahar B, Cummins EP, Brennan EP, Barry M, Belton O, Godson CG, Murphy EP, Crean D. McEvoy C, et al. Among authors: cummins ep. Front Immunol. 2017 Jan 23;8:7. doi: 10.3389/fimmu.2017.00007. eCollection 2017. Front Immunol. 2017. PMID: 28167941 Free PMC article.
71 results