Chibale K - Search Results

1

Strategies to Combat Multi-Drug Resistance in Tuberculosis.

Singh V, Chibale K. Singh V, et al. Among authors: chibale k. Acc Chem Res. 2021 May 18;54(10):2361-2376. doi: 10.1021/acs.accounts.0c00878. Epub 2021 Apr 22. Acc Chem Res. 2021. PMID: 33886255 Free PMC article. Review.

2

Application of multi-component reactions to antimalarial drug discovery. Part 1: Parallel synthesis and antiplasmodial activity of new 4-aminoquinoline Ugi adducts.

Musonda CC, Taylor D, Lehman J, Gut J, Rosenthal PJ, Chibale K. Musonda CC, et al. Among authors: chibale k. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3901-5. doi: 10.1016/j.bmcl.2004.05.063. Bioorg Med Chem Lett. 2004. PMID: 15225694

3

Synthesis, antimalarial and antitubercular activity of acetylenic chalcones.

Hans RH, Guantai EM, Lategan C, Smith PJ, Wan B, Franzblau SG, Gut J, Rosenthal PJ, Chibale K. Hans RH, et al. Among authors: chibale k. Bioorg Med Chem Lett. 2010 Feb 1;20(3):942-4. doi: 10.1016/j.bmcl.2009.12.062. Epub 2009 Dec 23. Bioorg Med Chem Lett. 2010. PMID: 20045640

4

Chloroquine resistance: proposed mechanisms and countermeasures.

Guantai E, Chibale K. Guantai E, et al. Among authors: chibale k. Curr Drug Deliv. 2010 Oct;7(4):312-23. doi: 10.2174/156720110793360577. Curr Drug Deliv. 2010. PMID: 20695842

5

Drug repositioning in the treatment of malaria and TB.

Nzila A, Ma Z, Chibale K. Nzila A, et al. Among authors: chibale k. Future Med Chem. 2011 Sep;3(11):1413-26. doi: 10.4155/fmc.11.95. Future Med Chem. 2011. PMID: 21879845 Review.

6

The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation of new arylamino quinoline derivatives.

Tukulula M, Little S, Gut J, Rosenthal PJ, Wan B, Franzblau SG, Chibale K. Tukulula M, et al. Among authors: chibale k. Eur J Med Chem. 2012 Nov;57:259-67. doi: 10.1016/j.ejmech.2012.08.047. Epub 2012 Sep 7. Eur J Med Chem. 2012. PMID: 23064162

7

Structure-activity relationship studies of orally active antimalarial 3,5-substituted 2-aminopyridines.

González Cabrera D, Douelle F, Younis Y, Feng TS, Le Manach C, Nchinda AT, Street LJ, Scheurer C, Kamber J, White KL, Montagnat OD, Ryan E, Katneni K, Zabiulla KM, Joseph JT, Bashyam S, Waterson D, Witty MJ, Charman SA, Wittlin S, Chibale K. González Cabrera D, et al. Among authors: chibale k. J Med Chem. 2012 Dec 27;55(24):11022-30. doi: 10.1021/jm301476b. Epub 2012 Dec 14. J Med Chem. 2012. PMID: 23189922

8

Antimalarial aminothiazoles and aminopyridines from phenotypic whole-cell screening of a SoftFocus(®) library.

Paquet T, Gordon R, Waterson D, Witty MJ, Chibale K. Paquet T, et al. Among authors: chibale k. Future Med Chem. 2012 Dec;4(18):2265-77. doi: 10.4155/fmc.12.176. Future Med Chem. 2012. PMID: 23234550

9

In silico comparison of antimycobacterial natural products with known antituberculosis drugs.

Espinoza-Moraga M, Njuguna NM, Mugumbate G, Caballero J, Chibale K. Espinoza-Moraga M, et al. Among authors: chibale k. J Chem Inf Model. 2013 Mar 25;53(3):649-60. doi: 10.1021/ci300467b. Epub 2013 Feb 22. J Chem Inf Model. 2013. PMID: 23410241

10

2,4-Diaminothienopyrimidines as orally active antimalarial agents.

González Cabrera D, Le Manach C, Douelle F, Younis Y, Feng TS, Paquet T, Nchinda AT, Street LJ, Taylor D, de Kock C, Wiesner L, Duffy S, White KL, Zabiulla KM, Sambandan Y, Bashyam S, Waterson D, Witty MJ, Charman SA, Avery VM, Wittlin S, Chibale K. González Cabrera D, et al. Among authors: chibale k. J Med Chem. 2014 Feb 13;57(3):1014-22. doi: 10.1021/jm401760c. Epub 2014 Jan 28. J Med Chem. 2014. PMID: 24446664

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