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AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.
Maiani E, Milletti G, Nazio F, Holdgaard SG, Bartkova J, Rizza S, Cianfanelli V, Lorente M, Simoneschi D, Di Marco M, D'Acunzo P, Di Leo L, Rasmussen R, Montagna C, Raciti M, De Stefanis C, Gabicagogeascoa E, Rona G, Salvador N, Pupo E, Merchut-Maya JM, Daniel CJ, Carinci M, Cesarini V, O'sullivan A, Jeong YT, Bordi M, Russo F, Campello S, Gallo A, Filomeni G, Lanzetti L, Sears RC, Hamerlik P, Bartolazzi A, Hynds RE, Pearce DR, Swanton C, Pagano M, Velasco G, Papaleo E, De Zio D, Maya-Mendoza A, Locatelli F, Bartek J, Cecconi F. Maiani E, et al. Among authors: campello s. Nature. 2021 Apr;592(7856):799-803. doi: 10.1038/s41586-021-03422-5. Epub 2021 Apr 14. Nature. 2021. PMID: 33854232 Free PMC article.
Reversible induction of mitophagy by an optogenetic bimodular system.
D'Acunzo P, Strappazzon F, Caruana I, Meneghetti G, Di Rita A, Simula L, Weber G, Del Bufalo F, Dalla Valle L, Campello S, Locatelli F, Cecconi F. D'Acunzo P, et al. Among authors: campello s. Nat Commun. 2019 Apr 4;10(1):1533. doi: 10.1038/s41467-019-09487-1. Nat Commun. 2019. PMID: 30948710 Free PMC article.
Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling.
Nazio F, Po A, Abballe L, Ballabio C, Diomedi Camassei F, Bordi M, Camera A, Caruso S, Caruana I, Pezzullo M, Ferraina C, Milletti G, Gianesello M, Reddel S, De Luca CD, Ceglie D, Marinelli S, Campello S, Papaleo E, Miele E, Cacchione A, Carai A, Vinci M, Velardi E, De Angelis B, Tiberi L, Quintarelli C, Mastronuzzi A, Ferretti E, Locatelli F, Cecconi F. Nazio F, et al. Among authors: campello s. Acta Neuropathol. 2021 Sep;142(3):537-564. doi: 10.1007/s00401-021-02347-7. Epub 2021 Jul 24. Acta Neuropathol. 2021. PMID: 34302498 Free PMC article.
Ho(a)xing autophagy to regulate development.
Campello S, Cecconi F. Campello S, et al. Dev Cell. 2014 Jan 13;28(1):3-4. doi: 10.1016/j.devcel.2013.12.018. Dev Cell. 2014. PMID: 24434134 Free article.
AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1.
Strappazzon F, Nazio F, Corrado M, Cianfanelli V, Romagnoli A, Fimia GM, Campello S, Nardacci R, Piacentini M, Campanella M, Cecconi F. Strappazzon F, et al. Among authors: campello s. Cell Death Differ. 2015 Mar;22(3):419-32. doi: 10.1038/cdd.2014.139. Epub 2014 Sep 12. Cell Death Differ. 2015. PMID: 25215947 Free PMC article.
S-nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy.
Rizza S, Cardaci S, Montagna C, Di Giacomo G, De Zio D, Bordi M, Maiani E, Campello S, Borreca A, Puca AA, Stamler JS, Cecconi F, Filomeni G. Rizza S, et al. Among authors: campello s. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3388-E3397. doi: 10.1073/pnas.1722452115. Epub 2018 Mar 26. Proc Natl Acad Sci U S A. 2018. PMID: 29581312 Free PMC article.
AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis.
Becher J, Simula L, Volpe E, Procaccini C, La Rocca C, D'Acunzo P, Cianfanelli V, Strappazzon F, Caruana I, Nazio F, Weber G, Gigantino V, Botti G, Ciccosanti F, Borsellino G, Campello S, Mandolesi G, De Bardi M, Fimia GM, D'Amelio M, Ruffini F, Furlan R, Centonze D, Martino G, Braghetta P, Chrisam M, Bonaldo P, Matarese G, Locatelli F, Battistini L, Cecconi F. Becher J, et al. Among authors: campello s. Dev Cell. 2018 Dec 3;47(5):592-607.e6. doi: 10.1016/j.devcel.2018.11.010. Dev Cell. 2018. PMID: 30513302 Free article.
Fanconi Anemia Genes, of Menders and Sweepers.
Campello S, Cecconi F. Campello S, et al. Dev Cell. 2016 May 23;37(4):299-300. doi: 10.1016/j.devcel.2016.05.011. Dev Cell. 2016. PMID: 27219059 Free article.
56 results