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Deletion of A44L, A46R and C12L Vaccinia Virus Genes from the MVA Genome Improved the Vector Immunogenicity by Modifying the Innate Immune Response Generating Enhanced and Optimized Specific T-Cell Responses.
Holgado MP, Falivene J, Maeto C, Amigo M, Pascutti MF, Vecchione MB, Bruttomesso A, Calamante G, Del Médico-Zajac MP, Gherardi MM. Holgado MP, et al. Among authors: calamante g. Viruses. 2016 May 23;8(5):139. doi: 10.3390/v8050139. Viruses. 2016. PMID: 27223301 Free PMC article.
Induction of Both Local Immune Response in Mice and Protection in a Rabbit Model by Intranasal Immunization with Modified Vaccinia Ankara Virus Expressing a Secreted Form of Bovine Herpesvirus 1 Glycoprotein D.
Del Medico Zajac MP, Zanetti FA, Esusy MS, Federico CR, Zabal O, Valera AR, Calamante G. Del Medico Zajac MP, et al. Among authors: calamante g. Viral Immunol. 2017 Jan/Feb;30(1):70-76. doi: 10.1089/vim.2016.0090. Epub 2016 Nov 3. Viral Immunol. 2017. PMID: 27809679
MVAΔ008 viral vector encoding the model protein OVA induces improved immune response against the heterologous antigen and equal levels of protection in a mice tumor model than the conventional MVA.
Del Médico Zajac MP, Molinari P, Gravisaco MJ, Maizon DO, Morón G, Gherardi MM, Calamante G. Del Médico Zajac MP, et al. Among authors: calamante g. Mol Immunol. 2021 Nov;139:115-122. doi: 10.1016/j.molimm.2021.08.004. Epub 2021 Sep 1. Mol Immunol. 2021. PMID: 34481269
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