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23 results

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A novel MYB::PAIP1 oncogenic fusion in pediatric blastic plasmacytoid dendritic cell neoplasm (BPDCN) is dependent on BCL2 expression and is sensitive to venetoclax.
Kosasih HJ, Healey G, Brennan MS, Bjelosevic S, Sadras T, Jalud FB, Ibnat T, Ng AP, Mayoh C, Mao J, Tax G, Ludlow LEA, Johnstone RW, Herold MJ, Khaw SL, de Bock CE, Ekert PG. Kosasih HJ, et al. Among authors: brennan ms. Hemasphere. 2024 Feb 14;8(2):e1. doi: 10.1002/hem3.1. eCollection 2024 Feb. Hemasphere. 2024. PMID: 38435422 Free PMC article. No abstract available.
MLL-TFE3: a novel and aggressive KMT2A fusion identified in infant leukemia.
Kosasih HJ, Davidson NM, Bjelosevic S, Morrish E, Brennan MS, Oshlack A, Johnstone RW, Brumatti G, Khaw SL, Ekert PG. Kosasih HJ, et al. Among authors: brennan ms. Blood Adv. 2020 Oct 13;4(19):4918-4923. doi: 10.1182/bloodadvances.2020002708. Blood Adv. 2020. PMID: 33035331 Free PMC article.
Loss of TRP53 reduces but does not overcome dependency of lymphoma cells on MCL-1.
Aubrey BJ, Brennan MS, Diepstraten ST, Wang Z, Chang C, Herold MJ, Strasser A, Kelly GL. Aubrey BJ, et al. Among authors: brennan ms. Cell Death Differ. 2022 May;29(5):1074-1076. doi: 10.1038/s41418-022-00946-9. Epub 2022 Jan 28. Cell Death Differ. 2022. PMID: 35091693 Free PMC article. No abstract available.
Characterisation of a novel A1-specific monoclonal antibody.
Lang MJ, Brennan MS, O'Reilly LA, Ottina E, Czabotar PE, Whitlock E, Fairlie WD, Tai L, Strasser A, Herold MJ. Lang MJ, et al. Among authors: brennan ms. Cell Death Dis. 2014 Dec 4;5(12):e1553. doi: 10.1038/cddis.2014.519. Cell Death Dis. 2014. PMID: 25476901 Free PMC article. No abstract available.
DNA repair processes are critical mediators of p53-dependent tumor suppression.
Janic A, Valente LJ, Wakefield MJ, Di Stefano L, Milla L, Wilcox S, Yang H, Tai L, Vandenberg CJ, Kueh AJ, Mizutani S, Brennan MS, Schenk RL, Lindqvist LM, Papenfuss AT, O'Connor L, Strasser A, Herold MJ. Janic A, et al. Among authors: brennan ms. Nat Med. 2018 Jul;24(7):947-953. doi: 10.1038/s41591-018-0043-5. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892060
Consequences of Zmat3 loss in c-MYC- and mutant KRAS-driven tumorigenesis.
Best SA, Vandenberg CJ, Abad E, Whitehead L, Guiu L, Ding S, Brennan MS, Strasser A, Herold MJ, Sutherland KD, Janic A. Best SA, et al. Among authors: brennan ms. Cell Death Dis. 2020 Oct 20;11(10):877. doi: 10.1038/s41419-020-03066-9. Cell Death Dis. 2020. PMID: 33082333 Free PMC article.
TRIM17 and TRIM28 antagonistically regulate the ubiquitination and anti-apoptotic activity of BCL2A1.
Lionnard L, Duc P, Brennan MS, Kueh AJ, Pal M, Guardia F, Mojsa B, Damiano MA, Mora S, Lassot I, Ravichandran R, Cochet C, Aouacheria A, Potts PR, Herold MJ, Desagher S, Kucharczak J. Lionnard L, et al. Among authors: brennan ms. Cell Death Differ. 2019 May;26(5):902-917. doi: 10.1038/s41418-018-0169-5. Epub 2018 Jul 24. Cell Death Differ. 2019. PMID: 30042493 Free PMC article.
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