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Selective Replacement of Cholesterol with Cationic Amphiphilic Drugs Enables the Design of Lipid Nanoparticles with Improved RNA Delivery.
Bogaert B, Debisschop A, Ehouarne T, Van Eeckhoutte HP, De Volder J, Jacobs A, Pottie E, De Rycke R, Crabbé A, Mestdagh P, Lentacker I, Brusselle GG, Stove C, Verstraelen S, Maes T, Bracke KR, De Smedt SC, Raemdonck K. Bogaert B, et al. Among authors: van eeckhoutte hp. Nano Lett. 2024 Mar 13;24(10):2961-2971. doi: 10.1021/acs.nanolett.3c03345. Epub 2024 Mar 4. Nano Lett. 2024. PMID: 38477058
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD.
Van Eeckhoutte HP, Donovan C, Kim RY, Conlon TM, Ansari M, Khan H, Jayaraman R, Hansbro NG, Dondelinger Y, Delanghe T, Beal AM, Geddes B, Bertin J, Vanden Berghe T, De Volder J, Maes T, Vandenabeele P, Vanaudenaerde BM, Deforce D, Škevin S, Van Nieuwerburgh F, Verhamme FM, Joos GF, Idrees S, Schiller HB, Yildirim AÖ, Faiz A, Bertrand MJM, Brusselle GG, Hansbro PM, Bracke KR. Van Eeckhoutte HP, et al. Eur Respir J. 2023 Apr 1;61(4):2201506. doi: 10.1183/13993003.01506-2022. Print 2023 Apr. Eur Respir J. 2023. PMID: 36549711
The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.
Günes Günsel G, Conlon TM, Jeridi A, Kim R, Ertüz Z, Lang NJ, Ansari M, Novikova M, Jiang D, Strunz M, Gaianova M, Hollauer C, Gabriel C, Angelidis I, Doll S, Pestoni JC, Edelmann SL, Kohlhepp MS, Guillot A, Bassler K, Van Eeckhoutte HP, Kayalar Ö, Konyalilar N, Kanashova T, Rodius S, Ballester-López C, Genes Robles CM, Smirnova N, Rehberg M, Agarwal C, Krikki I, Piavaux B, Verleden SE, Vanaudenaerde B, Königshoff M, Dittmar G, Bracke KR, Schultze JL, Watz H, Eickelberg O, Stoeger T, Burgstaller G, Tacke F, Heissmeyer V, Rinkevich Y, Bayram H, Schiller HB, Conrad M, Schneider R, Yildirim AÖ. Günes Günsel G, et al. Among authors: van eeckhoutte hp. Nat Commun. 2022 Mar 14;13(1):1303. doi: 10.1038/s41467-022-28809-4. Nat Commun. 2022. PMID: 35288557 Free PMC article.
Quantification and role of innate lymphoid cell subsets in Chronic Obstructive Pulmonary Disease.
Blomme EE, Provoost S, De Smet EG, De Grove KC, Van Eeckhoutte HP, De Volder J, Hansbro PM, Bonato M, Saetta M, Wijnant SR, Verhamme F, Joos GF, Bracke KR, Brusselle GG, Maes T. Blomme EE, et al. Among authors: van eeckhoutte hp. Clin Transl Immunology. 2021 Jun 5;10(6):e1287. doi: 10.1002/cti2.1287. eCollection 2021. Clin Transl Immunology. 2021. PMID: 34136217 Free PMC article.
Necroptosis Signaling Promotes Inflammation, Airway Remodeling, and Emphysema in Chronic Obstructive Pulmonary Disease.
Lu Z, Van Eeckhoutte HP, Liu G, Nair PM, Jones B, Gillis CM, Nalkurthi BC, Verhamme F, Buyle-Huybrecht T, Vandenabeele P, Vanden Berghe T, Brusselle GG, Horvat JC, Murphy JM, Wark PA, Bracke KR, Fricker M, Hansbro PM. Lu Z, et al. Among authors: van eeckhoutte hp. Am J Respir Crit Care Med. 2021 Sep 15;204(6):667-681. doi: 10.1164/rccm.202009-3442OC. Am J Respir Crit Care Med. 2021. PMID: 34133911
Metallothioneins alter macrophage phenotype and represent novel therapeutic targets for acetaminophen-induced liver injury.
Devisscher L, Van Campenhout S, Lefere S, Raevens S, Tilleman L, Van Nieuwerburgh F, Van Eeckhoutte HP, Hoorens A, Lynes MA, Geerts A, Laukens D, Van Vlierberghe H. Devisscher L, et al. Among authors: van eeckhoutte hp. J Leukoc Biol. 2022 Jan;111(1):123-133. doi: 10.1002/JLB.3A0820-527R. Epub 2021 Mar 16. J Leukoc Biol. 2022. PMID: 33724533
Innate lymphoid cells in isocyanate-induced asthma: role of microRNA-155.
Blomme EE, Provoost S, Bazzan E, Van Eeckhoutte HP, Roffel MP, Pollaris L, Bontinck A, Bonato M, Vandenbroucke L, Verhamme F, Joos GF, Cosio MG, Vanoirbeek JAJ, Brusselle GG, Saetta M, Maes T. Blomme EE, et al. Among authors: van eeckhoutte hp. Eur Respir J. 2020 Sep 24;56(3):1901289. doi: 10.1183/13993003.01289-2019. Print 2020 Sep. Eur Respir J. 2020. PMID: 32499335 Free article.
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