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Identification of Tse8 as a Type VI secretion system toxin from Pseudomonas aeruginosa that targets the bacterial transamidosome to inhibit protein synthesis in prey cells.
Nolan LM, Cain AK, Clamens T, Furniss RCD, Manoli E, Sainz-Polo MA, Dougan G, Albesa-Jové D, Parkhill J, Mavridou DAI, Filloux A. Nolan LM, et al. Among authors: sainz polo ma. Nat Microbiol. 2021 Sep;6(9):1199-1210. doi: 10.1038/s41564-021-00950-8. Epub 2021 Aug 19. Nat Microbiol. 2021. PMID: 34413503 Free PMC article.
Structural and kinetic insights reveal that the amino acid pair Gln-228/Asn-254 modulates the transfructosylating specificity of Schwanniomyces occidentalis β-fructofuranosidase, an enzyme that produces prebiotics.
Álvaro-Benito M, Sainz-Polo MA, González-Pérez D, González B, Plou FJ, Fernández-Lobato M, Sanz-Aparicio J. Álvaro-Benito M, et al. J Biol Chem. 2012 Jun 1;287(23):19674-86. doi: 10.1074/jbc.M112.355503. Epub 2012 Apr 16. J Biol Chem. 2012. PMID: 22511773 Free PMC article.
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