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Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC. Johnson MO, et al. Among authors: restifo np. Cell. 2018 Dec 13;175(7):1780-1795.e19. doi: 10.1016/j.cell.2018.10.001. Epub 2018 Nov 1. Cell. 2018. PMID: 30392958 Free PMC article.
Type 17 CD8+ T cells display enhanced antitumor immunity.
Hinrichs CS, Kaiser A, Paulos CM, Cassard L, Sanchez-Perez L, Heemskerk B, Wrzesinski C, Borman ZA, Muranski P, Restifo NP. Hinrichs CS, et al. Among authors: restifo np. Blood. 2009 Jul 16;114(3):596-9. doi: 10.1182/blood-2009-02-203935. Epub 2009 May 26. Blood. 2009. PMID: 19471017 Free PMC article.
Th17 cells are long lived and retain a stem cell-like molecular signature.
Muranski P, Borman ZA, Kerkar SP, Klebanoff CA, Ji Y, Sanchez-Perez L, Sukumar M, Reger RN, Yu Z, Kern SJ, Roychoudhuri R, Ferreyra GA, Shen W, Durum SK, Feigenbaum L, Palmer DC, Antony PA, Chan CC, Laurence A, Danner RL, Gattinoni L, Restifo NP. Muranski P, et al. Among authors: restifo np. Immunity. 2011 Dec 23;35(6):972-85. doi: 10.1016/j.immuni.2011.09.019. Epub 2011 Dec 15. Immunity. 2011. PMID: 22177921 Free PMC article.
Memoirs of a reincarnated T cell.
Crompton JG, Rao M, Restifo NP. Crompton JG, et al. Among authors: restifo np. Cell Stem Cell. 2013 Jan 3;12(1):6-8. doi: 10.1016/j.stem.2012.12.009. Cell Stem Cell. 2013. PMID: 23290132 Free PMC article.
Essentials of Th17 cell commitment and plasticity.
Muranski P, Restifo NP. Muranski P, et al. Among authors: restifo np. Blood. 2013 Mar 28;121(13):2402-14. doi: 10.1182/blood-2012-09-378653. Epub 2013 Jan 16. Blood. 2013. PMID: 23325835 Free PMC article. Review.
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.
Khor B, Gagnon JD, Goel G, Roche MI, Conway KL, Tran K, Aldrich LN, Sundberg TB, Paterson AM, Mordecai S, Dombkowski D, Schirmer M, Tan PH, Bhan AK, Roychoudhuri R, Restifo NP, O'Shea JJ, Medoff BD, Shamji AF, Schreiber SL, Sharpe AH, Shaw SY, Xavier RJ. Khor B, et al. Among authors: restifo np. Elife. 2015 May 22;4:e05920. doi: 10.7554/eLife.05920. Elife. 2015. PMID: 25998054 Free PMC article.
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Clever D, Roychoudhuri R, Constantinides MG, Askenase MH, Sukumar M, Klebanoff CA, Eil RL, Hickman HD, Yu Z, Pan JH, Palmer DC, Phan AT, Goulding J, Gattinoni L, Goldrath AW, Belkaid Y, Restifo NP. Clever D, et al. Among authors: restifo np. Cell. 2016 Aug 25;166(5):1117-1131.e14. doi: 10.1016/j.cell.2016.07.032. Cell. 2016. PMID: 27565342 Free PMC article.
Arginine Arms T Cells to Thrive and Survive.
Kishton RJ, Sukumar M, Restifo NP. Kishton RJ, et al. Among authors: restifo np. Cell Metab. 2016 Nov 8;24(5):647-648. doi: 10.1016/j.cmet.2016.10.019. Cell Metab. 2016. PMID: 27829132 Free PMC article.
Metabolic reprograming of anti-tumor immunity.
Sukumar M, Kishton RJ, Restifo NP. Sukumar M, et al. Among authors: restifo np. Curr Opin Immunol. 2017 Jun;46:14-22. doi: 10.1016/j.coi.2017.03.011. Epub 2017 Apr 13. Curr Opin Immunol. 2017. PMID: 28412583 Free PMC article. Review.
355 results