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AKAP13 couples GPCR signaling to mTORC1 inhibition.
Zhang S, Wang H, Melick CH, Jeong MH, Curukovic A, Tiwary S, Lama-Sherpa TD, Meng D, Servage KA, James NG, Jewell JL. Zhang S, et al. Among authors: jewell jl. PLoS Genet. 2021 Oct 21;17(10):e1009832. doi: 10.1371/journal.pgen.1009832. eCollection 2021 Oct. PLoS Genet. 2021. PMID: 34673774 Free PMC article.
mTOR signaling in stem and progenitor cells.
Meng D, Frank AR, Jewell JL. Meng D, et al. Among authors: jewell jl. Development. 2018 Jan 8;145(1):dev152595. doi: 10.1242/dev.152595. Development. 2018. PMID: 29311260 Free PMC article. Review.
Clearing debris.
Meng D, Jewell JL. Meng D, et al. Among authors: jewell jl. Nat Chem Biol. 2019 Aug;15(8):760-761. doi: 10.1038/s41589-019-0320-8. Nat Chem Biol. 2019. PMID: 31285594 Free PMC article.
Glutamine and asparagine activate mTORC1 independently of Rag GTPases.
Meng D, Yang Q, Wang H, Melick CH, Navlani R, Frank AR, Jewell JL. Meng D, et al. Among authors: jewell jl. J Biol Chem. 2020 Mar 6;295(10):2890-2899. doi: 10.1074/jbc.AC119.011578. Epub 2020 Feb 4. J Biol Chem. 2020. PMID: 32019866 Free PMC article.
Regulation of mTORC1 by Upstream Stimuli.
Melick CH, Jewell JL. Melick CH, et al. Among authors: jewell jl. Genes (Basel). 2020 Aug 25;11(9):989. doi: 10.3390/genes11090989. Genes (Basel). 2020. PMID: 32854217 Free PMC article. Review.
ArfGAP1 inhibits mTORC1 lysosomal localization and activation.
Meng D, Yang Q, Melick CH, Park BC, Hsieh TS, Curukovic A, Jeong MH, Zhang J, James NG, Jewell JL. Meng D, et al. Among authors: jewell jl. EMBO J. 2021 Jun 15;40(12):e106412. doi: 10.15252/embj.2020106412. Epub 2021 May 14. EMBO J. 2021. PMID: 33988249 Free PMC article.
41 results