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Sulfonyl-polyol N,N-dichloroamines with rapid, broad-spectrum antimicrobial activity.
Shiau TP, Low E, Kim B, Turtle ED, Francavilla C, O'Mahony DJ, Friedman L, D'Lima L, Jekle A, Debabov D, Zuck M, Alvarez NJ, Anderson M, Najafi RR, Jain RK. Shiau TP, et al. Among authors: anderson m. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5650-3. doi: 10.1016/j.bmcl.2013.08.027. Epub 2013 Aug 17. Bioorg Med Chem Lett. 2013. PMID: 23999044
Novel N-chloroheterocyclic antimicrobials.
Francavilla C, Turtle ED, Kim B, O'Mahony DJ, Shiau TP, Low E, Alvarez NJ, Celeri CE, D'Lima L, Friedman LC, Ruado FS, Xu P, Zuck ME, Anderson MB, Najafi RR, Jain RK. Francavilla C, et al. Bioorg Med Chem Lett. 2011 May 15;21(10):3029-33. doi: 10.1016/j.bmcl.2011.03.035. Epub 2011 Mar 16. Bioorg Med Chem Lett. 2011. PMID: 21459574
Novel 3-chlorooxazolidin-2-ones as antimicrobial agents.
Shiau TP, Turtle ED, Francavilla C, Alvarez NJ, Zuck M, Friedman L, O'Mahony DJ, Low E, Anderson MB, Najafi RR, Jain RK. Shiau TP, et al. Among authors: anderson mb. Bioorg Med Chem Lett. 2011 May 15;21(10):3025-8. doi: 10.1016/j.bmcl.2011.03.036. Epub 2011 Mar 21. Bioorg Med Chem Lett. 2011. PMID: 21470861
Structure stability/activity relationships of sulfone stabilized N,N-dichloroamines.
Low E, Kim B, Francavilla C, Shiau TP, Turtle ED, O'Mahony DJ, Alvarez N, Houchin A, Xu P, Zuck M, Celeri C, Anderson MB, Najafi RR, Jain RK. Low E, et al. Among authors: anderson mb. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3682-5. doi: 10.1016/j.bmcl.2011.04.084. Epub 2011 Apr 24. Bioorg Med Chem Lett. 2011. PMID: 21570284
NVC-422 inactivates Staphylococcus aureus toxins.
Jekle A, Yoon J, Zuck M, Najafi R, Wang L, Shiau T, Francavilla C, Rani SA, Eitzinger C, Nagl M, Anderson M, Debabov D. Jekle A, et al. Among authors: anderson m. Antimicrob Agents Chemother. 2013 Feb;57(2):924-9. doi: 10.1128/AAC.01945-12. Epub 2012 Dec 3. Antimicrob Agents Chemother. 2013. PMID: 23208720 Free PMC article.
NVC-422 topical gel for the treatment of impetigo.
Iovino SM, Krantz KD, Blanco DM, Fernández JA, Ocampo N, Najafi A, Memarzadeh B, Celeri C, Debabov D, Khosrovi B, Anderson M. Iovino SM, et al. Among authors: anderson m. Int J Clin Exp Pathol. 2011 Aug 15;4(6):587-95. Epub 2011 Jul 23. Int J Clin Exp Pathol. 2011. PMID: 21904634 Free PMC article. Clinical Trial.
8,020 results