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An extremely low frequency magnetic field attenuates insulin secretion from the insulinoma cell line, RIN-m.
Sakurai T, Satake A, Sumi S, Inoue K, Miyakoshi J. Sakurai T, et al. Bioelectromagnetics. 2004 Apr;25(3):160-6. doi: 10.1002/bem.10181. Bioelectromagnetics. 2004. PMID: 15042624
In this study, we investigated the effects of exposure to an extremely low frequency magnetic field (ELFMF) on hormone secretion from an islet derived insulinoma cell line, RIN-m. We stimulated RIN-m cells to secrete insulin under exposure to an ELFMF, using our est …
In this study, we investigated the effects of exposure to an extremely low frequency magnetic field (ELFMF) on hormone secretion from an isl …
Tyr-phosphorylation signals translocate RIN3, the small GTPase Rab5-GEF, to early endocytic vesicles.
Yoshikawa M, Kajiho H, Sakurai K, Minoda T, Nakagawa S, Kontani K, Katada T. Yoshikawa M, et al. Biochem Biophys Res Commun. 2008 Jul 18;372(1):168-72. doi: 10.1016/j.bbrc.2008.05.027. Epub 2008 May 16. Biochem Biophys Res Commun. 2008. PMID: 18486601
Rab5-GEFs share a conserved VPS9 domain for the GEF action, and RIN3 containing additional domains, such as Src-homology 2, RIN-family homology (RH), and Ras-association (RA), was identified as a new Rab5-GEF. ...Our present results suggest that a Ras GTPase(s) activated b …
Rab5-GEFs share a conserved VPS9 domain for the GEF action, and RIN3 containing additional domains, such as Src-homology 2, RIN-famil …
Characterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31.
Kajiho H, Sakurai K, Minoda T, Yoshikawa M, Nakagawa S, Fukushima S, Kontani K, Katada T. Kajiho H, et al. J Biol Chem. 2011 Jul 8;286(27):24364-73. doi: 10.1074/jbc.M110.172445. Epub 2011 May 17. J Biol Chem. 2011. PMID: 21586568 Free PMC article.
We investigated whether RIN family members act as guanine nucleotide exchange factors (GEFs) for the Rab5 subfamily on biochemical and cell morphological levels. ...We also found that serine to alanine substitutions in the sequences between SH2 and RIN family homolo …
We investigated whether RIN family members act as guanine nucleotide exchange factors (GEFs) for the Rab5 subfamily on biochemical an …
Molecular cloning of rat Pax4: identification of four isoforms in rat insulinoma cells.
Tokuyama Y, Yagui K, Sakurai K, Hashimoto N, Saito Y, Kanatsuka A. Tokuyama Y, et al. Biochem Biophys Res Commun. 1998 Jul 9;248(1):153-6. doi: 10.1006/bbrc.1998.8925. Biochem Biophys Res Commun. 1998. PMID: 9675102
Analysis of tissue distribution using Northern blotting and RT-PCR showed specific expression of Pax4 mRNA in pancreatic islets and RIN cells. RT-PCR confirmed that the mRNAs of four isoforms are expressed in RIN cells. ...
Analysis of tissue distribution using Northern blotting and RT-PCR showed specific expression of Pax4 mRNA in pancreatic islets and RIN …