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The following term was not found in PubMed: Renissa
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Cannabinoquinones: Synthesis and Biological Profile.
Caprioglio D, Mattoteia D, Taglialatela-Scafati O, Muñoz E, Appendino G. Caprioglio D, et al. Biomolecules. 2021 Jul 5;11(7):991. doi: 10.3390/biom11070991. Biomolecules. 2021. PMID: 34356614 Free PMC article. Review.
Neutral cannabinoids are oxidatively unstable and are converted into quinone derivatives by atmospheric- and/or chemical oxidative dearomatization. The study of cannabinoquinones has long been plagued by their lability toward additional oxidative degradation, but full subs …
Neutral cannabinoids are oxidatively unstable and are converted into quinone derivatives by atmospheric- and/or chemical oxidative de …
Antimalarial application of quinones: A recent update.
Patel OPS, Beteck RM, Legoabe LJ. Patel OPS, et al. Eur J Med Chem. 2021 Jan 15;210:113084. doi: 10.1016/j.ejmech.2020.113084. Epub 2020 Dec 5. Eur J Med Chem. 2021. PMID: 33333397 Review.
Several semi-synthetic derivatives of natural quinones, synthetic quinones (naphtho-/benzo-quinone, anthraquinones, thiazinoquinones), and quinone-based hybrids were explored for their in vitro and in vivo antimalarial activities. ...Therefore, we here …
Several semi-synthetic derivatives of natural quinones, synthetic quinones (naphtho-/benzo-quinone, anthraquinones, thi …
Natural sesquiterpene quinone/quinols: chemistry, biological activity, and synthesis.
Tian XH, Hong LL, Jiao WH, Lin HW. Tian XH, et al. Nat Prod Rep. 2023 Mar 22;40(3):718-749. doi: 10.1039/d2np00045h. Nat Prod Rep. 2023. PMID: 36636914 Review.
Covering: 2010 to 2021Sesquiterpene quinone/quinols (SQs) are characterized by a C15-sesquiterpenoid unit incorporating a C6-benzoquinone/quinol moiety. ...
Covering: 2010 to 2021Sesquiterpene quinone/quinols (SQs) are characterized by a C15-sesquiterpenoid unit incorporating a C6-benzoqui …
Formation and biological targets of botanical o-quinones.
Bolton JL, Dunlap TL, Dietz BM. Bolton JL, et al. Food Chem Toxicol. 2018 Oct;120:700-707. doi: 10.1016/j.fct.2018.07.050. Epub 2018 Jul 29. Food Chem Toxicol. 2018. PMID: 30063944 Free PMC article. Review.
Green tea contains catechins which are directly oxidized to o-quinones by various oxidative enzymes. Alternatively, phenolic botanicals could be o-hydroxylated by P450 to form catechols in vivo which are oxidized to o-quinones. Examples include, resveratrol which is …
Green tea contains catechins which are directly oxidized to o-quinones by various oxidative enzymes. Alternatively, phenolic botanica …
Quinone-based fluorophores for imaging biological processes.
Dias GG, King A, de Moliner F, Vendrell M, da Silva Júnior EN. Dias GG, et al. Chem Soc Rev. 2018 Jan 2;47(1):12-27. doi: 10.1039/c7cs00553a. Chem Soc Rev. 2018. PMID: 29099127 Review.
Quinones are privileged chemical structures playing crucial roles as redox and alkylating agents in a wide range of processes in cells. The broad functional array of quinones has prompted the development of new chemical approaches, including C-H bond activation and
Quinones are privileged chemical structures playing crucial roles as redox and alkylating agents in a wide range of processes in cell
Research advances in NQO1-responsive prodrugs and nanocarriers for cancer treatment.
Yang X, Duan J, Wu L. Yang X, et al. Future Med Chem. 2022 Mar;14(5):363-383. doi: 10.4155/fmc-2021-0289. Epub 2022 Feb 1. Future Med Chem. 2022. PMID: 35102756 Review.
NAD(P)H:quinine oxidoreductase (NQO1) is a class of flavoprotein enzymes commonly expressed in eukaryotic cells. It actively participates in the metabolism of various quinones and their in vivo bioactivation through electron reduction reactions. ...
NAD(P)H:quinine oxidoreductase (NQO1) is a class of flavoprotein enzymes commonly expressed in eukaryotic cells. It actively participates in …
Quinones as an Efficient Molecular Scaffold in the Antibacterial/Antifungal or Antitumoral Arsenal.
Dahlem Junior MA, Nguema Edzang RW, Catto AL, Raimundo JM. Dahlem Junior MA, et al. Int J Mol Sci. 2022 Nov 15;23(22):14108. doi: 10.3390/ijms232214108. Int J Mol Sci. 2022. PMID: 36430585 Free PMC article. Review.
Quinone-based compounds constitute several general classes of antibiotics that have long shown unwavering efficiency against both Gram-positive and Gram-negative microbial infections. ...Quinone-based antibiotics display different bioactive profiles depending on the
Quinone-based compounds constitute several general classes of antibiotics that have long shown unwavering efficiency against both Gra
Chemicals and Drugs Forming Reactive Quinone and Quinone Imine Metabolites.
Klopčič I, Dolenc MS. Klopčič I, et al. Chem Res Toxicol. 2019 Jan 22;32(1):1-34. doi: 10.1021/acs.chemrestox.8b00213. Epub 2018 Dec 14. Chem Res Toxicol. 2019. PMID: 30500181 Review.
Quinones and quinone imines are highly reactive metabolites (RMs) able to induce dangerous effects in vivo. ...However, the presence of quinones and quinone imines structures in compounds is not always responsible for a toxic effect. ...
Quinones and quinone imines are highly reactive metabolites (RMs) able to induce dangerous effects in vivo. ...However, the pr
Quinone-Based Drugs: An Important Class of Molecules in Medicinal Chemistry.
Ferreira VF, de Carvalho AS, Ferreira PG, Lima CGS, de C da Silva F. Ferreira VF, et al. Med Chem. 2021;17(10):1073-1085. doi: 10.2174/1573406416666201106104756. Med Chem. 2021. PMID: 33155925 Review.
BACKGROUND: Several quinones are on the pharmaceutical market as drugs for the treatment of several diseases. OBJECTIVE: The aim of this review was to provide an overview of the quinones that have become drugs for several therapeutic applications. ...
BACKGROUND: Several quinones are on the pharmaceutical market as drugs for the treatment of several diseases. OBJECTIVE: The aim of t …
Quinones: Biosynthesis, Characterization of (13) C Spectroscopical Data and Pharmacological Activities.
Gomes de Carvalho NK, Wellisson da Silva Mendes J, Martins da Costa JG. Gomes de Carvalho NK, et al. Chem Biodivers. 2023 Dec;20(12):e202301365. doi: 10.1002/cbdv.202301365. Epub 2023 Nov 20. Chem Biodivers. 2023. PMID: 37926679 Review.
Quinones are natural products widely distributed in nature, which are involved in stages of several vital biological processes, with mostly having a variety of pharmacological properties. The main groups comprising most of these compounds are benzoquinones, naphthoquinones
Quinones are natural products widely distributed in nature, which are involved in stages of several vital biological processes, with
96,123 results
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