von Itzstein M - Search Results

1

Repurposing the Ionophore, PBT2, for Treatment of Multidrug-Resistant Neisseria gonorrhoeae Infections.

Jen FE, Edwards JL, El-Deeb IM, Walker MJ, von Itzstein M, Jennings MP. Jen FE, et al. Among authors: von itzstein m. Antimicrob Agents Chemother. 2022 Sep 20;66(9):e0231821. doi: 10.1128/aac.02318-21. Epub 2022 Aug 18. Antimicrob Agents Chemother. 2022. PMID: 35980187 Free PMC article.

2

A versatile synthesis of "tafuramycin A": a potent anticancer and parasite attenuating agent.

El-Deeb IM, Rose FJ, Healy PC, von Itzstein M. El-Deeb IM, et al. Among authors: von itzstein m. Org Biomol Chem. 2014 Jun 28;12(24):4260-4. doi: 10.1039/c4ob00842a. Org Biomol Chem. 2014. PMID: 24838868

3

Exploring human parainfluenza virus type-1 hemagglutinin-neuraminidase as a target for inhibitor discovery.

El-Deeb IM, Guillon P, Winger M, Eveno T, Haselhorst T, Dyason JC, von Itzstein M. El-Deeb IM, et al. Among authors: von itzstein m. J Med Chem. 2014 Sep 25;57(18):7613-23. doi: 10.1021/jm500759v. Epub 2014 Sep 8. J Med Chem. 2014. PMID: 25198831

4

Structure-guided discovery of potent and dual-acting human parainfluenza virus haemagglutinin-neuraminidase inhibitors.

Guillon P, Dirr L, El-Deeb IM, Winger M, Bailly B, Haselhorst T, Dyason JC, von Itzstein M. Guillon P, et al. Among authors: von itzstein m. Nat Commun. 2014 Oct 20;5:5268. doi: 10.1038/ncomms6268. Nat Commun. 2014. PMID: 25327774 Free article.

5

Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors.

Ng PS, Böhm R, Hartley-Tassell LE, Steen JA, Wang H, Lukowski SW, Hawthorne PL, Trezise AE, Coloe PJ, Grimmond SM, Haselhorst T, von Itzstein M, Paton AW, Paton JC, Jennings MP. Ng PS, et al. Among authors: von itzstein m. Nat Commun. 2014 Dec 17;5:5750. doi: 10.1038/ncomms6750. Nat Commun. 2014. PMID: 25517696 Free PMC article.

6

The catalytic mechanism of human parainfluenza virus type 3 haemagglutinin-neuraminidase revealed.

Dirr L, El-Deeb IM, Guillon P, Carroux CJ, Chavas LM, von Itzstein M. Dirr L, et al. Among authors: von itzstein m. Angew Chem Int Ed Engl. 2015 Mar 2;54(10):2936-40. doi: 10.1002/anie.201412243. Epub 2015 Feb 10. Angew Chem Int Ed Engl. 2015. PMID: 25676091

7

A dual drug regimen synergistically blocks human parainfluenza virus infection.

Bailly B, Dirr L, El-Deeb IM, Altmeyer R, Guillon P, von Itzstein M. Bailly B, et al. Among authors: von itzstein m. Sci Rep. 2016 Apr 7;6:24138. doi: 10.1038/srep24138. Sci Rep. 2016. PMID: 27053240 Free PMC article.

8

Glycointeractions in bacterial pathogenesis.

Poole J, Day CJ, von Itzstein M, Paton JC, Jennings MP. Poole J, et al. Among authors: von itzstein m. Nat Rev Microbiol. 2018 Jul;16(7):440-452. doi: 10.1038/s41579-018-0007-2. Nat Rev Microbiol. 2018. PMID: 29674747 Review.

9

Exploring inhibitor structural features required to engage the 216-loop of human parainfluenza virus type-3 hemagglutinin-neuraminidase.

El-Deeb IM, Guillon P, Dirr L, von Itzstein M. El-Deeb IM, et al. Among authors: von itzstein m. Medchemcomm. 2016 Oct 5;8(1):130-134. doi: 10.1039/c6md00519e. eCollection 2017 Jan 1. Medchemcomm. 2016. PMID: 30108698 Free PMC article.

10

Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance.

Bohlmann L, De Oliveira DMP, El-Deeb IM, Brazel EB, Harbison-Price N, Ong CY, Rivera-Hernandez T, Ferguson SA, Cork AJ, Phan MD, Soderholm AT, Davies MR, Nimmo GR, Dougan G, Schembri MA, Cook GM, McEwan AG, von Itzstein M, McDevitt CA, Walker MJ. Bohlmann L, et al. Among authors: von itzstein m. mBio. 2018 Dec 11;9(6):e02391-18. doi: 10.1128/mBio.02391-18. mBio. 2018. PMID: 30538186 Free PMC article.

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