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Design and synthesis of novel N-acetylgalactosamine-terminated glycolipids for targeting of lipoproteins to the hepatic asialoglycoprotein receptor.
J Med Chem. 2004 Nov 4;47(23):5798-808. doi: 10.1021/jm049481d.
J Med Chem. 2004.
PMID: 15509179
Stimulation of liver-directed cholesterol flux in mice by novel N-acetylgalactosamine-terminated glycolipids with high affinity for the asialoglycoprotein receptor.
Rensen PC, Sliedregt LA, van Santbrink PJ, Ferns M, Schifferstein HN, van Leeuwen SH, Souverijn JH, van Berkel TJ, Biessen EA.
Rensen PC, et al. Among authors: van leeuwen sh.
Arterioscler Thromb Vasc Biol. 2006 Jan;26(1):169-75. doi: 10.1161/01.ATV.0000193620.98587.40. Epub 2005 Oct 27.
Arterioscler Thromb Vasc Biol. 2006.
PMID: 16254203
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Determination of the upper size limit for uptake and processing of ligands by the asialoglycoprotein receptor on hepatocytes in vitro and in vivo.
Rensen PC, Sliedregt LA, Ferns M, Kieviet E, van Rossenberg SM, van Leeuwen SH, van Berkel TJ, Biessen EA.
Rensen PC, et al. Among authors: van leeuwen sh.
J Biol Chem. 2001 Oct 5;276(40):37577-84. doi: 10.1074/jbc.M101786200. Epub 2001 Jul 30.
J Biol Chem. 2001.
PMID: 11479285
Free article.
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Rational optimization of a short human P-selectin-binding peptide leads to nanomolar affinity antagonists.
Appeldoorn CC, Molenaar TJ, Bonnefoy A, van Leeuwen SH, Vandervoort PA, Hoylaerts MF, van Berkel TJ, Biessen EA.
Appeldoorn CC, et al. Among authors: van leeuwen sh.
J Biol Chem. 2003 Mar 21;278(12):10201-7. doi: 10.1074/jbc.M209267200. Epub 2003 Jan 13.
J Biol Chem. 2003.
PMID: 12525501
Free article.
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P-selectin as a candidate target in atherosclerosis.
Molenaar TJ, Twisk J, de Haas SA, Peterse N, Vogelaar BJ, van Leeuwen SH, Michon IN, van Berkel TJ, Kuiper J, Biessen EA.
Molenaar TJ, et al. Among authors: van leeuwen sh.
Biochem Pharmacol. 2003 Sep 1;66(5):859-66. doi: 10.1016/s0006-2952(03)00387-3.
Biochem Pharmacol. 2003.
PMID: 12948867
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