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Apoptotic and antioxidant effects in HCT-116 colorectal carcinoma cells by a spiro-acridine compound, AMTAC-06.
Duarte SS, Silva DKF, Lisboa TMH, Gouveia RG, de Andrade CCN, de Sousa VM, Ferreira RC, de Moura RO, Gomes JNS, da Silva PM, de Lourdes Assunção Araújo de Azevedo F, Keesen TSL, Gonçalves JCR, Batista LM, Sobral MV. Duarte SS, et al. Among authors: de moura ro, de andrade ccn, de lourdes assuncao araujo de azevedo f, de sousa vm. Pharmacol Rep. 2022 Jun;74(3):545-554. doi: 10.1007/s43440-022-00357-0. Epub 2022 Mar 17. Pharmacol Rep. 2022. PMID: 35297003
Synthesis, DNA and protein interactions and human topoisomerase inhibition of novel Spiroacridine derivatives.
Gouveia RG, Ribeiro AG, Segundo MÂSP, de Oliveira JF, de Lima MDCA, de Lima Souza TRC, de Almeida SMV, de Moura RO. Gouveia RG, et al. Among authors: de almeida smv, de moura ro, de lima souza trc, de oliveira jf, de lima mdca. Bioorg Med Chem. 2018 Dec 1;26(22):5911-5921. doi: 10.1016/j.bmc.2018.10.038. Epub 2018 Oct 29. Bioorg Med Chem. 2018. PMID: 30420325
Anticancer Effect of a Spiro-acridine Compound Involves Immunomodulatory and Anti-angiogenic Actions.
Duarte SS, Silva DKF, Lisboa TMH, Gouveia RG, Ferreira RC, DE Moura RO, DA Silva JM, DE Almeida Lima É, Rodrigues-Mascarenhas S, DA Silva PM, Farias DF, DA Costa Ribeiro Souza JA, DE Paula Medeiros KC, GonÇalves JCR, Sobral MV. Duarte SS, et al. Among authors: de moura ro, de paula medeiros kc, de almeida lima e. Anticancer Res. 2020 Sep;40(9):5049-5057. doi: 10.21873/anticanres.14508. Anticancer Res. 2020. PMID: 32878793
In vitro anti-Leishmania activity and molecular docking of spiro-acridine compounds as potential multitarget agents against Leishmania infantum.
Almeida FS, Sousa GLS, Rocha JC, Ribeiro FF, de Oliveira MR, de Lima Grisi TCS, Araújo DAM, de C Nobre MS, Castro RN, Amaral IPG, Keesen TSL, de Moura RO. Almeida FS, et al. Among authors: de moura ro, de oliveira mr, de lima grisi tcs, de c nobre ms. Bioorg Med Chem Lett. 2021 Oct 1;49:128289. doi: 10.1016/j.bmcl.2021.128289. Epub 2021 Jul 24. Bioorg Med Chem Lett. 2021. PMID: 34311084
Cytotoxicity of a new spiro-acridine derivative: modulation of cellular antioxidant state and induction of cell cycle arrest and apoptosis in HCT-116 colorectal carcinoma.
de Sousa VM, Duarte SS, Silva DKF, Ferreira RC, de Moura RO, Segundo MASP, Farias D, Vieira L, Gonçalves JCR, Sobral MV. de Sousa VM, et al. Among authors: de moura ro. Naunyn Schmiedebergs Arch Pharmacol. 2024 Mar;397(3):1901-1913. doi: 10.1007/s00210-023-02686-0. Epub 2023 Sep 7. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 37676494 No abstract available.
44 results