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Development of a fluorogenic ADAMTS-7 substrate.
Santamaria S, Buemi F, Nuti E, Cuffaro D, De Vita E, Tuccinardi T, Rossello A, Howell S, Mehmood S, Snijders AP, de Groot R. Santamaria S, et al. Among authors: de vita e, de groot r. J Enzyme Inhib Med Chem. 2021 Dec;36(1):2160-2169. doi: 10.1080/14756366.2021.1983808. J Enzyme Inhib Med Chem. 2021. PMID: 34587841 Free PMC article.
Monoclonal antibodies against metzincin targets.
Santamaria S, de Groot R. Santamaria S, et al. Among authors: de groot r. Br J Pharmacol. 2019 Jan;176(1):52-66. doi: 10.1111/bph.14186. Epub 2018 Apr 2. Br J Pharmacol. 2019. PMID: 29488211 Free PMC article. Review.
ADAMTS proteases in cardiovascular physiology and disease.
Santamaria S, de Groot R. Santamaria S, et al. Among authors: de groot r. Open Biol. 2020 Dec;10(12):200333. doi: 10.1098/rsob.200333. Epub 2020 Dec 23. Open Biol. 2020. PMID: 33352066 Free PMC article. Review.
Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide.
Santamaria S, Cuffaro D, Nuti E, Ciccone L, Tuccinardi T, Liva F, D'Andrea F, de Groot R, Rossello A, Ahnström J. Santamaria S, et al. Among authors: de groot r. Sci Rep. 2021 Jan 13;11(1):949. doi: 10.1038/s41598-020-80294-1. Sci Rep. 2021. PMID: 33441904 Free PMC article.
Crystal structure and substrate-induced activation of ADAMTS13.
Petri A, Kim HJ, Xu Y, de Groot R, Li C, Vandenbulcke A, Vanhoorelbeke K, Emsley J, Crawley JTB. Petri A, et al. Among authors: de groot r. Nat Commun. 2019 Aug 22;10(1):3781. doi: 10.1038/s41467-019-11474-5. Nat Commun. 2019. PMID: 31439947 Free PMC article.
835 results