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Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies.
Kennedy KM, de Goffau MC, Perez-Muñoz ME, Arrieta MC, Bäckhed F, Bork P, Braun T, Bushman FD, Dore J, de Vos WM, Earl AM, Eisen JA, Elovitz MA, Ganal-Vonarburg SC, Gänzle MG, Garrett WS, Hall LJ, Hornef MW, Huttenhower C, Konnikova L, Lebeer S, Macpherson AJ, Massey RC, McHardy AC, Koren O, Lawley TD, Ley RE, O'Mahony L, O'Toole PW, Pamer EG, Parkhill J, Raes J, Rattei T, Salonen A, Segal E, Segata N, Shanahan F, Sloboda DM, Smith GCS, Sokol H, Spector TD, Surette MG, Tannock GW, Walker AW, Yassour M, Walter J. Kennedy KM, et al. Among authors: de goffau mc. Nature. 2023 Jan;613(7945):639-649. doi: 10.1038/s41586-022-05546-8. Epub 2023 Jan 25. Nature. 2023. PMID: 36697862 Review.
Human placenta has no microbiome but can contain potential pathogens.
de Goffau MC, Lager S, Sovio U, Gaccioli F, Cook E, Peacock SJ, Parkhill J, Charnock-Jones DS, Smith GCS. de Goffau MC, et al. Nature. 2019 Aug;572(7769):329-334. doi: 10.1038/s41586-019-1451-5. Epub 2019 Jul 31. Nature. 2019. PMID: 31367035 Free PMC article.
Over-celling fetal microbial exposure.
Kennedy KM, Bellissimo CJ, Breznik JA, Barrett J, Braun T, Bushman FD, De Goffau M, Elovitz MA, Heimesaat MM, Konnikova L, Koren O, Parry S, Rossi L, Segata N, Simmons RA, Surette MG, Walter J, Sloboda DM. Kennedy KM, et al. Cell. 2021 Nov 24;184(24):5839-5841. doi: 10.1016/j.cell.2021.10.026. Cell. 2021. PMID: 34822779 Free article. No abstract available.
Recognizing the reagent microbiome.
de Goffau MC, Lager S, Salter SJ, Wagner J, Kronbichler A, Charnock-Jones DS, Peacock SJ, Smith GCS, Parkhill J. de Goffau MC, et al. Nat Microbiol. 2018 Aug;3(8):851-853. doi: 10.1038/s41564-018-0202-y. Nat Microbiol. 2018. PMID: 30046175 No abstract available.
Fetal inheritance of chromosomally integrated human herpesvirus 6 predisposes the mother to pre-eclampsia.
Gaccioli F, Lager S, de Goffau MC, Sovio U, Dopierala J, Gong S, Cook E, Sharkey A, Moffett A, Lee WK, Delles C, Venturini C, Breuer J, Parkhill J, Peacock SJ, Charnock-Jones DS, Smith GCS. Gaccioli F, et al. Among authors: de goffau mc. Nat Microbiol. 2020 Jul;5(7):901-908. doi: 10.1038/s41564-020-0711-3. Epub 2020 May 4. Nat Microbiol. 2020. PMID: 32367053 Free PMC article.
63 results