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Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients with chronic lymphocytic leukemia.
Quinten E, Sepúlveda-Yáñez JH, Koning MT, Eken JA, Pfeifer D, Nteleah V, De Groen RAL, Saravia DA, Knijnenburg J, Stuivenberg-Bleijswijk HE, Pantic M, Agathangelidis A, Keppler-Hafkemeyer A, Van Bergen CAM, Uribe-Paredes R, Stamatopoulos K, Vermaat JSP, Zirlik K, Navarrete MA, Jumaa H, Veelken H. Quinten E, et al. Among authors: zirlik k. Haematologica. 2024 Mar 1;109(3):824-834. doi: 10.3324/haematol.2022.282542. Haematologica. 2024. PMID: 37439337 Free PMC article.
Evidence for idiotype-directed immunosurveillance is restricted to follicular lymphoma and attributable to somatic hypermutation.
Papaioannou D, Strothmeyer AM, Dühren-von Minden M, Keppler-Hafkemeyer A, Zirlik K, Mikesch K, van Bergen CA, Navarrete MA, Veelken H. Papaioannou D, et al. Among authors: zirlik k. Haematologica. 2015 Apr;100(4):e143-6. doi: 10.3324/haematol.2014.111252. Epub 2015 Jan 23. Haematologica. 2015. PMID: 25616573 Free PMC article. No abstract available.
Idelalisib.
Zirlik K, Veelken H. Zirlik K, et al. Recent Results Cancer Res. 2018;212:243-264. doi: 10.1007/978-3-319-91439-8_12. Recent Results Cancer Res. 2018. PMID: 30069634 Review.
Microenvironmental stromal cells abrogate NF-κB inhibitor-induced apoptosis in chronic lymphocytic leukemia.
Simon-Gabriel CP, Foerster K, Saleem S, Bleckmann D, Benkisser-Petersen M, Thornton N, Umezawa K, Decker S, Burger M, Veelken H, Claus R, Dierks C, Duyster J, Zirlik K. Simon-Gabriel CP, et al. Among authors: zirlik k. Haematologica. 2018 Jan;103(1):136-147. doi: 10.3324/haematol.2017.165381. Epub 2017 Nov 9. Haematologica. 2018. PMID: 29122993 Free PMC article.
PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1).
Decker S, Finter J, Forde AJ, Kissel S, Schwaller J, Mack TS, Kuhn A, Gray N, Follo M, Jumaa H, Burger M, Zirlik K, Pfeifer D, Miduturu CV, Eibel H, Veelken H, Dierks C. Decker S, et al. Among authors: zirlik k. Mol Cancer Ther. 2014 May;13(5):1231-45. doi: 10.1158/1535-7163.MCT-13-0575-T. Epub 2014 Mar 21. Mol Cancer Ther. 2014. PMID: 24659821
Spleen Tyrosine Kinase Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia.
Benkisser-Petersen M, Buchner M, Dörffel A, Dühren-von-Minden M, Claus R, Kläsener K, Leberecht K, Burger M, Dierks C, Jumaa H, Malavasi F, Reth M, Veelken H, Duyster J, Zirlik K. Benkisser-Petersen M, et al. Among authors: zirlik k. PLoS One. 2016 Dec 30;11(12):e0169159. doi: 10.1371/journal.pone.0169159. eCollection 2016. PLoS One. 2016. PMID: 28036404 Free PMC article.
47 results