Evidence for idiotype-directed immunosurveillance is restricted to follicular lymphoma and attributable to somatic hypermutation

Haematologica. 2015 Apr;100(4):e143-6. doi: 10.3324/haematol.2014.111252. Epub 2015 Jan 23.

Authors

Dimitrios Papaioannou¹, Anna-Maria Strothmeyer¹, Marcus Dühren-von Minden¹, Andrea Keppler-Hafkemeyer¹, Katja Zirlik¹, Kristina Mikesch¹, Cornelis A M van Bergen², Marcelo A Navarrete³, Hendrik Veelken⁴

Affiliations

¹ Department of Hematology/Oncology, University Medical Center Freiburg, Germany.
² Department of Hematology, Leiden University Medical Center, The Netherlands.
³ School of Medicine, University of Magallanes, Punta Arenas, Chile.
⁴ Department of Hematology, Leiden University Medical Center, The Netherlands j.h.veelken@lumc.nl.

No abstract available

Keywords: B-cell lymphoma; BCR-directed immunosurveillance; follicular lymphoma; somatic hypermutation.

Publication types

Letter

MeSH terms

HLA Antigens / genetics
HLA Antigens / immunology
Humans
Immunoglobulin Idiotypes / immunology*
Immunologic Surveillance*
Lymphoma, Follicular / genetics*
Lymphoma, Follicular / immunology*
Somatic Hypermutation, Immunoglobulin*
T-Lymphocyte Subsets / immunology
T-Lymphocyte Subsets / metabolism

Substances

HLA Antigens
Immunoglobulin Idiotypes