Zhuang L - Search Results

1

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer.

Liu X, Olszewski K, Zhang Y, Lim EW, Shi J, Zhang X, Zhang J, Lee H, Koppula P, Lei G, Zhuang L, You MJ, Fang B, Li W, Metallo CM, Poyurovsky MV, Gan B. Liu X, et al. Among authors: zhuang l. Nat Cell Biol. 2020 Apr;22(4):476-486. doi: 10.1038/s41556-020-0496-x. Epub 2020 Mar 30. Nat Cell Biol. 2020. PMID: 32231310 Free PMC article.

2

FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis.

Gan B, Lim C, Chu G, Hua S, Ding Z, Collins M, Hu J, Jiang S, Fletcher-Sananikone E, Zhuang L, Chang M, Zheng H, Wang YA, Kwiatkowski DJ, Kaelin WG Jr, Signoretti S, DePinho RA. Gan B, et al. Among authors: zhuang l. Cancer Cell. 2010 Nov 16;18(5):472-84. doi: 10.1016/j.ccr.2010.10.019. Cancer Cell. 2010. PMID: 21075312 Free PMC article.

3

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

Gan B, Hu J, Jiang S, Liu Y, Sahin E, Zhuang L, Fletcher-Sananikone E, Colla S, Wang YA, Chin L, Depinho RA. Gan B, et al. Among authors: zhuang l. Nature. 2010 Dec 2;468(7324):701-4. doi: 10.1038/nature09595. Nature. 2010. PMID: 21124456 Free PMC article.

4

The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress.

Lin A, Yao J, Zhuang L, Wang D, Han J, Lam EW, Gan B. Lin A, et al. Among authors: zhuang l. Oncogene. 2014 Jun 12;33(24):3183-94. doi: 10.1038/onc.2013.273. Epub 2013 Jul 15. Oncogene. 2014. PMID: 23851496 Free PMC article.

5

FoxO transcription factors promote AKT Ser473 phosphorylation and renal tumor growth in response to pharmacologic inhibition of the PI3K-AKT pathway.

Lin A, Piao HL, Zhuang L, Sarbassov dos D, Ma L, Gan B. Lin A, et al. Among authors: zhuang l. Cancer Res. 2014 Mar 15;74(6):1682-93. doi: 10.1158/0008-5472.CAN-13-1729. Epub 2014 Jan 21. Cancer Res. 2014. PMID: 24448243 Free PMC article.

6

BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21.

Lee H, Dai F, Zhuang L, Xiao ZD, Kim J, Zhang Y, Ma L, You MJ, Wang Z, Gan B. Lee H, et al. Among authors: zhuang l. Oncotarget. 2016 Apr 12;7(15):19134-46. doi: 10.18632/oncotarget.8102. Oncotarget. 2016. PMID: 26992241 Free PMC article.

7

LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress.

Liu X, Xiao ZD, Han L, Zhang J, Lee SW, Wang W, Lee H, Zhuang L, Chen J, Lin HK, Wang J, Liang H, Gan B. Liu X, et al. Among authors: zhuang l. Nat Cell Biol. 2016 Apr;18(4):431-42. doi: 10.1038/ncb3328. Epub 2016 Mar 21. Nat Cell Biol. 2016. PMID: 26999735 Free PMC article.

8

Long non-coding RNAs in cancer metabolism.

Xiao ZD, Zhuang L, Gan B. Xiao ZD, et al. Among authors: zhuang l. Bioessays. 2016 Oct;38(10):991-6. doi: 10.1002/bies.201600110. Epub 2016 Aug 23. Bioessays. 2016. PMID: 27550823 Free PMC article. Review.

9

NBR2: A former junk gene emerges as a key player in tumor suppression.

Xiao ZD, Liu X, Zhuang L, Gan B. Xiao ZD, et al. Among authors: zhuang l. Mol Cell Oncol. 2016 May 24;3(4):e1187322. doi: 10.1080/23723556.2016.1187322. eCollection 2016 Jul. Mol Cell Oncol. 2016. PMID: 27652330 Free PMC article.

10

BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response.

Dai F, Lee H, Zhang Y, Zhuang L, Yao H, Xi Y, Xiao ZD, You MJ, Li W, Su X, Gan B. Dai F, et al. Among authors: zhuang l. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3192-3197. doi: 10.1073/pnas.1619588114. Epub 2017 Mar 8. Proc Natl Acad Sci U S A. 2017. PMID: 28275095 Free PMC article.

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