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Inhibition of S-adenosyl-L-homocysteine hydrolase induces immunosuppression.
Wu QL, Fu YF, Zhou WL, Wang JX, Feng YH, Liu J, Xu JY, He PL, Zhou R, Tang W, Wang GF, Zhou Y, Yang YF, Ding J, Li XY, Chen XR, Yuan C, Lawson BR, Zuo JP. Wu QL, et al. Among authors: zhou y, zhou wl, zhou r. J Pharmacol Exp Ther. 2005 May;313(2):705-11. doi: 10.1124/jpet.104.080416. Epub 2005 Jan 7. J Pharmacol Exp Ther. 2005. PMID: 15640397
7'-(3',4'-dihydroxyphenyl)-N-[(4-methoxyphenyl)ethyl]propenamide (Z23), an effective compound from the Chinese herb medicine Fissistigma oldhamii (Hemsl.) Merr, suppresses T cell-mediated immunity in vitro and in vivo.
Hu XD, Zhong XG, Zhang XH, Zhang YN, Zheng ZP, Zhou Y, Tang W, Yang Y, Yang YF, Hu LH, Zuo JP. Hu XD, et al. Among authors: zhou y. Life Sci. 2007 Dec 14;81(25-26):1677-84. doi: 10.1016/j.lfs.2007.10.004. Epub 2007 Oct 23. Life Sci. 2007. PMID: 18022200
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