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Why Molnupiravir Fails in Hospitalized Patients.
Brown AN, Lang Y, Zhou J, Franco EJ, Hanrahan KC, Bulitta JB, Drusano GL. Brown AN, et al. Among authors: zhou j. mBio. 2022 Dec 20;13(6):e0291622. doi: 10.1128/mbio.02916-22. Epub 2022 Nov 14. mBio. 2022. PMID: 36374076 Free PMC article.
Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five β-Lactams Simultaneously in Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter cloacae.
Kim TH, Tao X, Moya B, Jiao Y, Basso KB, Zhou J, Lang Y, Sutaria DS, Zavascki AP, Barth AL, Reeve SM, Schweizer HP, Deveson Lucas D, Boyce JD, Bonomo RA, Lee RE, Shin BS, Louie A, Drusano GL, Bulitta JB. Kim TH, et al. Among authors: zhou j. mBio. 2020 Feb 11;11(1):e03189-19. doi: 10.1128/mBio.03189-19. mBio. 2020. PMID: 32047131 Free PMC article.
First Penicillin-Binding Protein Occupancy Patterns for 15 β-Lactams and β-Lactamase Inhibitors in Mycobacterium abscessus.
Sayed ARM, Shah NR, Basso KB, Kamat M, Jiao Y, Moya B, Sutaria DS, Lang Y, Tao X, Liu W, Shin E, Zhou J, Werkman C, Louie A, Drusano GL, Bulitta JB. Sayed ARM, et al. Among authors: zhou j. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e01956-20. doi: 10.1128/AAC.01956-20. Print 2020 Dec 16. Antimicrob Agents Chemother. 2020. PMID: 33106266 Free PMC article.
Combating Multidrug-Resistant Bacteria by Integrating a Novel Target Site Penetration and Receptor Binding Assay Platform Into Translational Modeling.
Lang Y, Shah NR, Tao X, Reeve SM, Zhou J, Moya B, Sayed ARM, Dharuman S, Oyer JL, Copik AJ, Fleischer BA, Shin E, Werkman C, Basso KB, Deveson Lucas D, Sutaria DS, Mégroz M, Kim TH, Loudon-Hossler V, Wright A, Jimenez-Nieves RH, Wallace MJ, Cadet KC, Jiao Y, Boyce JD, LoVullo ED, Schweizer HP, Bonomo RA, Bharatham N, Tsuji BT, Landersdorfer CB, Norris MH, Soo Shin B, Louie A, Balasubramanian V, Lee RE, Drusano GL, Bulitta JB. Lang Y, et al. Among authors: zhou j. Clin Pharmacol Ther. 2021 Apr;109(4):1000-1020. doi: 10.1002/cpt.2205. Epub 2021 Mar 24. Clin Pharmacol Ther. 2021. PMID: 33576025 Free PMC article.
Generating Genotype-Specific Aminoglycoside Combinations with Ceftazidime/Avibactam for KPC-Producing Klebsiella pneumoniae.
Huang Y, Sokolowski K, Rana A, Singh N, Wang J, Chen K, Lang Y, Zhou J, Kadiyala N, Krapp F, Ozer EA, Hauser AR, Li J, Bulitta JB, Bulman ZP. Huang Y, et al. Among authors: zhou j. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0069221. doi: 10.1128/AAC.00692-21. Epub 2021 Aug 17. Antimicrob Agents Chemother. 2021. PMID: 34152820 Free PMC article.
Simulated Intravenous versus Inhaled Tobramycin with or without Intravenous Ceftazidime Evaluated against Hypermutable Pseudomonas aeruginosa via a Dynamic Biofilm Model and Mechanism-Based Modeling.
Bilal H, Tait JR, Lang Y, Zhou J, Bergen PJ, Peleg AY, Bulitta JB, Oliver A, Nation RL, Landersdorfer CB. Bilal H, et al. Among authors: zhou j. Antimicrob Agents Chemother. 2022 Mar 15;66(3):e0220321. doi: 10.1128/aac.02203-21. Epub 2022 Jan 18. Antimicrob Agents Chemother. 2022. PMID: 35041509 Free PMC article.
Effect of Different Piperacillin-Tazobactam Dosage Regimens on Synergy of the Combination with Tobramycin against Pseudomonas aeruginosa for the Pharmacokinetics of Critically Ill Patients in a Dynamic Infection Model.
Tait JR, Bilal H, Rogers KE, Lang Y, Kim TH, Zhou J, Wallis SC, Bulitta JB, Kirkpatrick CMJ, Paterson DL, Lipman J, Bergen PJ, Roberts JA, Nation RL, Landersdorfer CB. Tait JR, et al. Among authors: zhou j. Antibiotics (Basel). 2022 Jan 13;11(1):101. doi: 10.3390/antibiotics11010101. Antibiotics (Basel). 2022. PMID: 35052977 Free PMC article.
Mechanistic Insights to Combating NDM- and CTX-M-Coproducing Klebsiella pneumoniae by Targeting Cell Wall Synthesis and Outer Membrane Integrity.
Smith NM, Boissonneault KR, Chen L, Petraitis V, Petraitiene R, Tao X, Zhou J, Lang Y, Kavaliauskas P, Bulman ZP, Holden PN, Cha R, Bulitta JB, Kreiswirth BN, Walsh TJ, Tsuji BT. Smith NM, et al. Among authors: zhou j. Antimicrob Agents Chemother. 2022 Sep 20;66(9):e0052722. doi: 10.1128/aac.00527-22. Epub 2022 Aug 4. Antimicrob Agents Chemother. 2022. PMID: 35924913 Free PMC article.
Ceftolozane/tazobactam plus tobramycin against free-floating and biofilm bacteria of hypermutable Pseudomonas aeruginosa epidemic strains: Resistance mechanisms and synergistic activity.
Agyeman AA, López-Causapé C, Rogers KE, Lucas DD, Cortés-Lara S, Gomis-Font MA, Fraile-Ribot P, Figuerola J, Lang Y, Franklyn ERT, Lee WL, Zhou J, Zhang Y, Bulitta JB, Boyce JD, Nation RL, Oliver A, Landersdorfer CB. Agyeman AA, et al. Among authors: zhou j. Int J Antimicrob Agents. 2023 Sep;62(3):106887. doi: 10.1016/j.ijantimicag.2023.106887. Epub 2023 Jun 12. Int J Antimicrob Agents. 2023. PMID: 37315906
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