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Study of Structure-Activity Relationships of the Marine Alkaloid Fascaplysin and Its Derivatives as Potent Anticancer Agents.
Zhidkov ME, Kaune M, Kantemirov AV, Smirnova PA, Spirin PV, Sidorova MA, Stadnik SA, Shyrokova EY, Kaluzhny DN, Tryapkin OA, Busenbender T, Hauschild J, Rohlfing T, Prassolov VS, Bokemeyer C, Graefen M, von Amsberg G, Dyshlovoy SA. Zhidkov ME, et al. Mar Drugs. 2022 Mar 2;20(3):185. doi: 10.3390/md20030185. Mar Drugs. 2022. PMID: 35323484 Free PMC article.
Alkaloids of fascaplysin are effective conventional chemotherapeutic drugs, inhibiting the proliferation of C6 glioma cells and causing their death in vitro.
Bryukhovetskiy I, Lyakhova I, Mischenko P, Milkina E, Zaitsev S, Khotimchenko Y, Bryukhovetskiy A, Polevshchikov A, Kudryavtsev I, Khotimchenko M, Zhidkov M. Bryukhovetskiy I, et al. Oncol Lett. 2017 Feb;13(2):738-746. doi: 10.3892/ol.2016.5478. Epub 2016 Dec 9. Oncol Lett. 2017. PMID: 28356953 Free PMC article.
New 6,6-Spiroketal from the Alga-Derived Fungus Penicillium lividum.
Zhuravleva OI, Sobolevskaya MP, Denisenko VA, Kirichuk NN, Zhidkov ME, Ermakova SP, Kim NY, Antonov AS, Leshchenko EV, Afiyatullov SSh. Zhuravleva OI, et al. Among authors: zhidkov me. Nat Prod Commun. 2016 Feb;11(2):207-10. Nat Prod Commun. 2016. PMID: 27032203
Efficacy and Mechanism of Action of Marine Alkaloid 3,10-Dibromofascaplysin in Drug-Resistant Prostate Cancer Cells.
Dyshlovoy SA, Kaune M, Hauschild J, Kriegs M, Hoffer K, Busenbender T, Smirnova PA, Zhidkov ME, Poverennaya EV, Oh-Hohenhorst SJ, Spirin PV, Prassolov VS, Tilki D, Bokemeyer C, Graefen M, von Amsberg G. Dyshlovoy SA, et al. Among authors: zhidkov me. Mar Drugs. 2020 Dec 1;18(12):609. doi: 10.3390/md18120609. Mar Drugs. 2020. PMID: 33271756 Free PMC article.
13 results