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Extracellular fluid viscosity enhances cell migration and cancer dissemination.
Bera K, Kiepas A, Godet I, Li Y, Mehta P, Ifemembi B, Paul CD, Sen A, Serra SA, Stoletov K, Tao J, Shatkin G, Lee SJ, Zhang Y, Boen A, Mistriotis P, Gilkes DM, Lewis JD, Fan CM, Feinberg AP, Valverde MA, Sun SX, Konstantopoulos K. Bera K, et al. Among authors: zhang y. Nature. 2022 Nov;611(7935):365-373. doi: 10.1038/s41586-022-05394-6. Epub 2022 Nov 2. Nature. 2022. PMID: 36323783 Free PMC article.
Confinement hinders motility by inducing RhoA-mediated nuclear influx, volume expansion, and blebbing.
Mistriotis P, Wisniewski EO, Bera K, Keys J, Li Y, Tuntithavornwat S, Law RA, Perez-Gonzalez NA, Erdogmus E, Zhang Y, Zhao R, Sun SX, Kalab P, Lammerding J, Konstantopoulos K. Mistriotis P, et al. Among authors: zhang y. J Cell Biol. 2019 Dec 2;218(12):4093-4111. doi: 10.1083/jcb.201902057. Epub 2019 Nov 5. J Cell Biol. 2019. PMID: 31690619 Free PMC article.
Polarized NHE1 and SWELL1 regulate migration direction, efficiency and metastasis.
Zhang Y, Li Y, Thompson KN, Stoletov K, Yuan Q, Bera K, Lee SJ, Zhao R, Kiepas A, Wang Y, Mistriotis P, Serra SA, Lewis JD, Valverde MA, Martin SS, Sun SX, Konstantopoulos K. Zhang Y, et al. Nat Commun. 2022 Oct 17;13(1):6128. doi: 10.1038/s41467-022-33683-1. Nat Commun. 2022. PMID: 36253369 Free PMC article.
Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion.
Tran AT, Wisniewski EO, Mistriotis P, Stoletov K, Parlani M, Amitrano A, Ifemembi B, Lee SJ, Bera K, Zhang Y, Tuntithavornwat S, Afthinos A, Kiepas A, Jamieson JJ, Zuo Y, Habib D, Wu PH, Martin SS, Gerecht S, Gu L, Lewis JD, Kalab P, Friedl P, Konstantopoulos K. Tran AT, et al. Among authors: zhang y. Res Sq [Preprint]. 2024 Jan 10:rs.3.rs-3640969. doi: 10.21203/rs.3.rs-3640969/v1. Res Sq. 2024. PMID: 38260442 Free PMC article. Preprint.
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