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Psoralen accelerates bone fracture healing by activating both osteoclasts and osteoblasts.
Zhang T, Han W, Zhao K, Yang W, Lu X, Jia Y, Qin A, Qian Y. Zhang T, et al. FASEB J. 2019 Apr;33(4):5399-5410. doi: 10.1096/fj.201801797R. Epub 2019 Jan 31. FASEB J. 2019. PMID: 30702934
Taken together, our findings indicate that psoralen accelerates bone fracture healing through activation of osteoclasts and osteoblasts via ERK signaling and has potential as a novel drug in the orthopedic clinic for the treatment of bone fractures.-Zhang, T., Han, …
Taken together, our findings indicate that psoralen accelerates bone fracture healing through activation of osteoclasts and osteoblasts via …
Anacardic acid inhibits RANKL-induced osteoclastogenesis in vitro and prevents ovariectomy-induced bone loss in vivo.
Zhao K, Jia Y, Peng J, Pang C, Zhang T, Han W, Jiang J, Lu X, Zhu J, Qian Y. Zhao K, et al. Among authors: zhang t. FASEB J. 2019 Aug;33(8):9100-9115. doi: 10.1096/fj.201802575RR. Epub 2019 May 3. FASEB J. 2019. PMID: 31050917
Mechanistically, anacardic acid disrupts the phosphorylation of TGF-beta activated kinase 1 and subsequently suppresses multiple receptor activator of NF-kappaB ligand-induced signaling cascades, ultimately inhibiting the induction and activation of the crucial osteoclast transcr …
Mechanistically, anacardic acid disrupts the phosphorylation of TGF-beta activated kinase 1 and subsequently suppresses multiple receptor ac …
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