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Screening of the Promising Direct Thrombin Inhibitors from Haematophagous Organisms. Part I: Recombinant Analogues and Their Antithrombotic Activity In Vitro.
Biomedicines. 2021 Dec 22;10(1):11. doi: 10.3390/biomedicines10010011.
Biomedicines. 2021.
PMID: 35052692
Free PMC article.
An explanation for the narrow carbohydrate substrate specificity of adenine phosphoribosyltransferase from Thermus thermophilus from the model of the enzyme, substrate, and magnesium cation cofactor complex.
Zayats EA, Timofeev VI, Kostromina MA, Esipov RS.
Zayats EA, et al.
J Biomol Struct Dyn. 2019 Oct;37(17):4460-4464. doi: 10.1080/07391102.2018.1550020. Epub 2018 Dec 31.
J Biomol Struct Dyn. 2019.
PMID: 30451097
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Multi-Enzymatic Cascades in the Synthesis of Modified Nucleosides: Comparison of the Thermophilic and Mesophilic Pathways.
Fateev IV, Kostromina MA, Abramchik YA, Eletskaya BZ, Mikheeva OO, Lukoshin DD, Zayats EA, Berzina MY, Dorofeeva EV, Paramonov AS, Kayushin AL, Konstantinova ID, Esipov RS.
Fateev IV, et al. Among authors: zayats ea.
Biomolecules. 2021 Apr 16;11(4):586. doi: 10.3390/biom11040586.
Biomolecules. 2021.
PMID: 33923608
Free PMC article.
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Synthesis of 2-chloropurine ribosides with chiral amino acid amides at C6 and their evaluation as A1 adenosine receptor agonists.
Berzina MY, Eletskaya BZ, Kayushin AL, Dorofeeva EV, Lutonina OI, Fateev IV, Paramonov AS, Kostromina MA, Zayats EA, Abramchik YA, Maltsev DV, Naumenko LV, Taran AS, Yakovlev DS, Spasov AA, Miroshnikov AI, Esipov RS, Konstantinova ID.
Berzina MY, et al. Among authors: zayats ea.
Bioorg Chem. 2022 Sep;126:105878. doi: 10.1016/j.bioorg.2022.105878. Epub 2022 May 18.
Bioorg Chem. 2022.
PMID: 35660725
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Rational Mutagenesis in the Lid Domain of Ribokinase from E. coli Results in an Order of Magnitude Increase in Activity towards D-arabinose.
Zayats EA, Fateev IV, Kostromina MA, Abramchik YA, Lykoshin DD, Yurovskaya DO, Timofeev VI, Berzina MY, Eletskaya BZ, Konstantinova ID, Esipov RS.
Zayats EA, et al.
Int J Mol Sci. 2022 Oct 19;23(20):12540. doi: 10.3390/ijms232012540.
Int J Mol Sci. 2022.
PMID: 36293391
Free PMC article.
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Unified Methodology for the Primary Preclinical In Vivo Screening of New Anticoagulant Pharmaceutical Agents from Hematophagous Organisms.
Kostromina MA, Tukhovskaya EA, Shaykhutdinova ER, Palikova YA, Palikov VA, Slashcheva GA, Ismailova AM, Kravchenko IN, Dyachenko IA, Zayats EA, Abramchik YA, Murashev AN, Esipov RS.
Kostromina MA, et al. Among authors: zayats ea.
Int J Mol Sci. 2024 Apr 3;25(7):3986. doi: 10.3390/ijms25073986.
Int J Mol Sci. 2024.
PMID: 38612796
Free PMC article.
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