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Bile salt hydrolase catalyses formation of amine-conjugated bile acids.
Rimal B, Collins SL, Tanes CE, Rocha ER, Granda MA, Solanki S, Hoque NJ, Gentry EC, Koo I, Reilly ER, Hao F, Paudel D, Singh V, Yan T, Kim MS, Bittinger K, Zackular JP, Krausz KW, Desai D, Amin S, Coleman JP, Shah YM, Bisanz JE, Gonzalez FJ, Vanden Heuvel JP, Wu GD, Zemel BS, Dorrestein PC, Weinert EE, Patterson AD. Rimal B, et al. Among authors: zackular jp. Nature. 2024 Feb;626(8000):859-863. doi: 10.1038/s41586-023-06990-w. Epub 2024 Feb 7. Nature. 2024. PMID: 38326609 Free PMC article.
Liberation of host heme by Clostridioides difficile-mediated damage enhances Enterococcus faecalis fitness during infection.
Smith AB, Specker JT, Hewlett KK, Scoggins TR 4th, Knight M, Lustig AM, Li Y, Evans KM, Guo Y, She Q, Christopher MW, Garrett TJ, Moustafa AM, Van Tyne D, Prentice BM, Zackular JP. Smith AB, et al. Among authors: zackular jp. mBio. 2024 Jan 16;15(1):e0165623. doi: 10.1128/mbio.01656-23. Epub 2023 Dec 11. mBio. 2024. PMID: 38078767 Free PMC article.
Intestinal epithelial autophagy is required for the regenerative benefit of calorie restriction.
Williams PA, Naughton KE, Simon LA, Soto GE, Parham LR, Ma X, Danan CH, Hu W, Friedman ES, McMillan EA, Mehta H, Stoltz MA, Ocaña JS, Zackular JP, Bittinger K, Whelan KA, Karakasheva TA, Hamilton KE. Williams PA, et al. Among authors: zackular jp. Am J Physiol Gastrointest Liver Physiol. 2023 May 1;324(5):G354-G368. doi: 10.1152/ajpgi.00248.2022. Epub 2023 Feb 28. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 36852920 Free PMC article.
Enterococci enhance Clostridioides difficile pathogenesis.
Smith AB, Jenior ML, Keenan O, Hart JL, Specker J, Abbas A, Rangel PC, Di C, Green J, Bustin KA, Gaddy JA, Nicholson MR, Laut C, Kelly BJ, Matthews ML, Evans DR, Van Tyne D, Furth EE, Papin JA, Bushman FD, Erlichman J, Baldassano RN, Silverman MA, Dunny GM, Prentice BM, Skaar EP, Zackular JP. Smith AB, et al. Among authors: zackular jp. Nature. 2022 Nov;611(7937):780-786. doi: 10.1038/s41586-022-05438-x. Epub 2022 Nov 16. Nature. 2022. PMID: 36385534 Free PMC article.
41 results