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A bioisosteric approach to the discovery of novel N-aryl-N'-[4-(aryloxy)cyclohexyl]squaramide-based activators of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation.
Kwak J, Kim MJ, Kim S, Park GB, Jo J, Jeong M, Kang S, Moon S, Bang S, An H, Hwang S, Kim MS, Yoo JW, Moon HR, Chang W, Chung KW, Jeong JY, Yun H. Kwak J, et al. Among authors: yun h. Eur J Med Chem. 2022 Sep 5;239:114501. doi: 10.1016/j.ejmech.2022.114501. Epub 2022 May 29. Eur J Med Chem. 2022. PMID: 35716517
Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis.
Chang DJ, An H, Kim KS, Kim HH, Jung J, Lee JM, Kim NJ, Han YT, Yun H, Lee S, Lee G, Lee S, Lee JS, Cha JH, Park JH, Park JW, Lee SC, Kim SG, Kim JH, Lee HY, Kim KW, Suh YG. Chang DJ, et al. Among authors: yun h. J Med Chem. 2012 Dec 27;55(24):10863-84. doi: 10.1021/jm301488q. Epub 2012 Dec 7. J Med Chem. 2012. PMID: 23186287
2,709 results