Young RA - Search Results

1

BET bromodomain inhibition as a therapeutic strategy to target c-Myc.

Delmore JE, Issa GC, Lemieux ME, Rahl PB, Shi J, Jacobs HM, Kastritis E, Gilpatrick T, Paranal RM, Qi J, Chesi M, Schinzel AC, McKeown MR, Heffernan TP, Vakoc CR, Bergsagel PL, Ghobrial IM, Richardson PG, Young RA, Hahn WC, Anderson KC, Kung AL, Bradner JE, Mitsiades CS. Delmore JE, et al. Among authors: young ra. Cell. 2011 Sep 16;146(6):904-17. doi: 10.1016/j.cell.2011.08.017. Epub 2011 Sep 1. Cell. 2011. PMID: 21889194 Free PMC article.

2

The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress.

Damelin M, Simon I, Moy TI, Wilson B, Komili S, Tempst P, Roth FP, Young RA, Cairns BR, Silver PA. Damelin M, et al. Among authors: young ra. Mol Cell. 2002 Mar;9(3):563-73. doi: 10.1016/s1097-2765(02)00475-6. Mol Cell. 2002. PMID: 11931764 Free article.

3

Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity.

Ng HH, Robert F, Young RA, Struhl K. Ng HH, et al. Among authors: young ra. Mol Cell. 2003 Mar;11(3):709-19. doi: 10.1016/s1097-2765(03)00092-3. Mol Cell. 2003. PMID: 12667453 Free article.

4

Binding of pRB to the PHD protein RBP2 promotes cellular differentiation.

Benevolenskaya EV, Murray HL, Branton P, Young RA, Kaelin WG Jr. Benevolenskaya EV, et al. Among authors: young ra. Mol Cell. 2005 Jun 10;18(6):623-35. doi: 10.1016/j.molcel.2005.05.012. Mol Cell. 2005. PMID: 15949438 Free article.

5

Divergent transcription from active promoters.

Seila AC, Calabrese JM, Levine SS, Yeo GW, Rahl PB, Flynn RA, Young RA, Sharp PA. Seila AC, et al. Among authors: young ra. Science. 2008 Dec 19;322(5909):1849-51. doi: 10.1126/science.1162253. Epub 2008 Dec 4. Science. 2008. PMID: 19056940 Free PMC article.

6

SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state.

Bilodeau S, Kagey MH, Frampton GM, Rahl PB, Young RA. Bilodeau S, et al. Among authors: young ra. Genes Dev. 2009 Nov 1;23(21):2484-9. doi: 10.1101/gad.1837309. Genes Dev. 2009. PMID: 19884255 Free PMC article.

7

c-Myc regulates transcriptional pause release.

Rahl PB, Lin CY, Seila AC, Flynn RA, McCuine S, Burge CB, Sharp PA, Young RA. Rahl PB, et al. Among authors: young ra. Cell. 2010 Apr 30;141(3):432-45. doi: 10.1016/j.cell.2010.03.030. Cell. 2010. PMID: 20434984 Free PMC article.

8

DHODH modulates transcriptional elongation in the neural crest and melanoma.

White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahl PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, Granter S, Young RA, Morrison S, Wheeler GN, Zon LI. White RM, et al. Among authors: young ra. Nature. 2011 Mar 24;471(7339):518-22. doi: 10.1038/nature09882. Nature. 2011. PMID: 21430780 Free PMC article.

9

Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells.

Giraud M, Yoshida H, Abramson J, Rahl PB, Young RA, Mathis D, Benoist C. Giraud M, et al. Among authors: young ra. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):535-40. doi: 10.1073/pnas.1119351109. Epub 2011 Dec 27. Proc Natl Acad Sci U S A. 2012. PMID: 22203960 Free PMC article.

10

Functional association of Gdown1 with RNA polymerase II poised on human genes.

Cheng B, Li T, Rahl PB, Adamson TE, Loudas NB, Guo J, Varzavand K, Cooper JJ, Hu X, Gnatt A, Young RA, Price DH. Cheng B, et al. Among authors: young ra. Mol Cell. 2012 Jan 13;45(1):38-50. doi: 10.1016/j.molcel.2011.10.022. Mol Cell. 2012. PMID: 22244331 Free PMC article.

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