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Charge Interactions in a Highly Charge-Depleted Protein.
Hervø-Hansen S, Højgaard C, Johansson KE, Wang Y, Wahni K, Young D, Messens J, Teilum K, Lindorff-Larsen K, Winther JR. Hervø-Hansen S, et al. Among authors: young d. J Am Chem Soc. 2021 Feb 17;143(6):2500-2508. doi: 10.1021/jacs.0c10789. Epub 2021 Feb 2. J Am Chem Soc. 2021. PMID: 33529004
The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis.
Rosado LA, Wahni K, Degiacomi G, Pedre B, Young D, de la Rubia AG, Boldrin F, Martens E, Marcos-Pascual L, Sancho-Vaello E, Albesa-Jové D, Provvedi R, Martin C, Makarov V, Versées W, Verniest G, Guerin ME, Mateos LM, Manganelli R, Messens J. Rosado LA, et al. Among authors: young d. J Biol Chem. 2017 Aug 11;292(32):13097-13110. doi: 10.1074/jbc.M117.797837. Epub 2017 Jun 15. J Biol Chem. 2017. PMID: 28620052 Free PMC article.
Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2 sensing.
Pedre B, Young D, Charlier D, Mourenza Á, Rosado LA, Marcos-Pascual L, Wahni K, Martens E, G de la Rubia A, Belousov VV, Mateos LM, Messens J. Pedre B, et al. Among authors: young d. Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11623-E11632. doi: 10.1073/pnas.1807954115. Epub 2018 Nov 21. Proc Natl Acad Sci U S A. 2018. PMID: 30463959 Free PMC article.
Ultrasensitive Genetically Encoded Indicator for Hydrogen Peroxide Identifies Roles for the Oxidant in Cell Migration and Mitochondrial Function.
Pak VV, Ezeriņa D, Lyublinskaya OG, Pedre B, Tyurin-Kuzmin PA, Mishina NM, Thauvin M, Young D, Wahni K, Martínez Gache SA, Demidovich AD, Ermakova YG, Maslova YD, Shokhina AG, Eroglu E, Bilan DS, Bogeski I, Michel T, Vriz S, Messens J, Belousov VV. Pak VV, et al. Among authors: young d. Cell Metab. 2020 Mar 3;31(3):642-653.e6. doi: 10.1016/j.cmet.2020.02.003. Cell Metab. 2020. PMID: 32130885 Free PMC article.
Protein Promiscuity in H2O2 Signaling.
Young D, Pedre B, Ezeriņa D, De Smet B, Lewandowska A, Tossounian MA, Bodra N, Huang J, Astolfi Rosado L, Van Breusegem F, Messens J. Young D, et al. Antioxid Redox Signal. 2019 Apr 1;30(10):1285-1324. doi: 10.1089/ars.2017.7013. Epub 2018 Jun 6. Antioxid Redox Signal. 2019. PMID: 29635930 Review.
5,314 results