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Base editing-mediated splicing correction therapy for spinal muscular atrophy.
Lin X, Chen H, Lu YQ, Hong S, Hu X, Gao Y, Lai LL, Li JJ, Wang Z, Ying W, Ma L, Wang N, Zuo E, Yang H, Chen WJ. Lin X, et al. Among authors: ying w. Cell Res. 2020 Jun;30(6):548-550. doi: 10.1038/s41422-020-0304-y. Epub 2020 Mar 24. Cell Res. 2020. PMID: 32210360 Free PMC article. No abstract available.
Disruption of splicing-regulatory elements using CRISPR/Cas9 to rescue spinal muscular atrophy in human iPSCs and mice.
Li JJ, Lin X, Tang C, Lu YQ, Hu X, Zuo E, Li H, Ying W, Sun Y, Lai LL, Chen HZ, Guo XX, Zhang QJ, Wu S, Zhou C, Shen X, Wang Q, Lin MT, Ma LX, Wang N, Krainer AR, Shi L, Yang H, Chen WJ. Li JJ, et al. Among authors: ying w. Natl Sci Rev. 2019 Sep 3;7(1):92-101. doi: 10.1093/nsr/nwz131. eCollection 2020 Jan. Natl Sci Rev. 2019. PMID: 34691481 Free PMC article.
High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects.
Tong H, Huang J, Xiao Q, He B, Dong X, Liu Y, Yang X, Han D, Wang Z, Wang X, Ying W, Zhang R, Wei Y, Xu C, Zhou Y, Li Y, Cai M, Wang Q, Xue M, Li G, Fang K, Zhang H, Yang H. Tong H, et al. Among authors: ying w. Nat Biotechnol. 2023 Jan;41(1):108-119. doi: 10.1038/s41587-022-01419-7. Epub 2022 Aug 11. Nat Biotechnol. 2023. PMID: 35953673
CRISPR/Cas9-mediated targeted chromosome elimination.
Zuo E, Huo X, Yao X, Hu X, Sun Y, Yin J, He B, Wang X, Shi L, Ping J, Wei Y, Ying W, Wei W, Liu W, Tang C, Li Y, Hu J, Yang H. Zuo E, et al. Among authors: ying w. Genome Biol. 2017 Nov 24;18(1):224. doi: 10.1186/s13059-017-1354-4. Genome Biol. 2017. PMID: 29178945 Free PMC article.
One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs.
Zuo E, Cai YJ, Li K, Wei Y, Wang BA, Sun Y, Liu Z, Liu J, Hu X, Wei W, Huo X, Shi L, Tang C, Liang D, Wang Y, Nie YH, Zhang CC, Yao X, Wang X, Zhou C, Ying W, Wang Q, Chen RC, Shen Q, Xu GL, Li J, Sun Q, Xiong ZQ, Yang H. Zuo E, et al. Among authors: ying w. Cell Res. 2017 Jul;27(7):933-945. doi: 10.1038/cr.2017.81. Epub 2017 Jun 6. Cell Res. 2017. PMID: 28585534 Free PMC article.
834 results