Yarwood SJ - Search Results

1

Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1.

Beck EM, Parnell E, Cowley A, Porter A, Gillespie J, Robinson J, Robinson L, Pannifer AD, Hamon V, Jones P, Morrison A, McElroy S, Timmerman M, Rutjes H, Mahajan P, Wiejak J, Luchowska-Stańska U, Morgan D, Barker G, Rehmann H, Yarwood SJ. Beck EM, et al. Among authors: yarwood sj. Cells. 2019 Nov 12;8(11):1425. doi: 10.3390/cells8111425. Cells. 2019. PMID: 31726720 Free PMC article.

2

Regulation of the inflammatory response of vascular endothelial cells by EPAC1.

Parnell E, Smith BO, Palmer TM, Terrin A, Zaccolo M, Yarwood SJ. Parnell E, et al. Among authors: yarwood sj. Br J Pharmacol. 2012 May;166(2):434-46. doi: 10.1111/j.1476-5381.2011.01808.x. Br J Pharmacol. 2012. PMID: 22145651 Free PMC article. Review.

3

Extracellular signal-regulated kinase mitogen-activated protein kinase-dependent SOCS-3 gene induction requires c-Jun, signal transducer and activator of transcription 3, and specificity protein 3 transcription factors.

Wiejak J, Dunlop J, Gao S, Borland G, Yarwood SJ. Wiejak J, et al. Among authors: yarwood sj. Mol Pharmacol. 2012 May;81(5):657-68. doi: 10.1124/mol.111.076976. Epub 2012 Feb 6. Mol Pharmacol. 2012. PMID: 22311708

4

Genomic analysis of the role of transcription factor C/EBPδ in the regulation of cell behaviour on nanometric grooves.

Wiejak J, Tsimbouri PM, Herzyk P, Dalby MJ, Hamilton G, Yarwood SJ. Wiejak J, et al. Among authors: yarwood sj. Biomaterials. 2013 Mar;34(8):1967-79. doi: 10.1016/j.biomaterials.2012.11.036. Epub 2012 Dec 13. Biomaterials. 2013. PMID: 23245923 Free PMC article.

5

Flavanoids induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene and suppress IL-6-activated signal transducer and activator of transcription 3 (STAT3) activation in vascular endothelial cells.

Wiejak J, Dunlop J, Mackay SP, Yarwood SJ. Wiejak J, et al. Among authors: yarwood sj. Biochem J. 2013 Sep 1;454(2):283-93. doi: 10.1042/BJ20130481. Biochem J. 2013. PMID: 23782265 Free PMC article.

6

The role of c-Jun in controlling the EPAC1-dependent induction of the SOCS3 gene in HUVECs.

Wiejak J, Dunlop J, Yarwood SJ. Wiejak J, et al. Among authors: yarwood sj. FEBS Lett. 2014 May 2;588(9):1556-61. doi: 10.1016/j.febslet.2014.02.038. Epub 2014 Mar 11. FEBS Lett. 2014. PMID: 24631457 Free PMC article.

7

Interactions between Epac1 and ezrin in the control of endothelial barrier function.

Parnell E, Yarwood SJ. Parnell E, et al. Among authors: yarwood sj. Biochem Soc Trans. 2014 Apr;42(2):274-8. doi: 10.1042/BST20130271. Biochem Soc Trans. 2014. PMID: 24646230 Review.

8

The cAMP sensors, EPAC1 and EPAC2, display distinct subcellular distributions despite sharing a common nuclear pore localisation signal.

Parnell E, Smith BO, Yarwood SJ. Parnell E, et al. Among authors: yarwood sj. Cell Signal. 2015 May;27(5):989-96. doi: 10.1016/j.cellsig.2015.02.009. Epub 2015 Feb 12. Cell Signal. 2015. PMID: 25683912 Free PMC article.

9

The future of EPAC-targeted therapies: agonism versus antagonism.

Parnell E, Palmer TM, Yarwood SJ. Parnell E, et al. Among authors: yarwood sj. Trends Pharmacol Sci. 2015 Apr;36(4):203-14. doi: 10.1016/j.tips.2015.02.003. Epub 2015 Mar 3. Trends Pharmacol Sci. 2015. PMID: 25744542 Free PMC article. Review.

10

Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells.

Parnell E, Koschinski A, Zaccolo M, Cameron RT, Baillie GS, Baillie GL, Porter A, McElroy SP, Yarwood SJ. Parnell E, et al. Among authors: yarwood sj. Biochim Biophys Acta. 2015 Jul;1853(7):1749-58. doi: 10.1016/j.bbamcr.2015.04.009. Epub 2015 Apr 23. Biochim Biophys Acta. 2015. PMID: 25913012 Free PMC article.

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