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Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.
Dev H, Chiang TW, Lescale C, de Krijger I, Martin AG, Pilger D, Coates J, Sczaniecka-Clift M, Wei W, Ostermaier M, Herzog M, Lam J, Shea A, Demir M, Wu Q, Yang F, Fu B, Lai Z, Balmus G, Belotserkovskaya R, Serra V, O'Connor MJ, Bruna A, Beli P, Pellegrini L, Caldas C, Deriano L, Jacobs JJL, Galanty Y, Jackson SP. Dev H, et al. Among authors: wu q. Nat Cell Biol. 2018 Aug;20(8):954-965. doi: 10.1038/s41556-018-0140-1. Epub 2018 Jul 18. Nat Cell Biol. 2018. PMID: 30022119 Free PMC article.
Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining.
Cabello-Lobato MJ, Jenner M, Cisneros-Aguirre M, Brüninghoff K, Sandy Z, da Costa IC, Jowitt TA, Loch CM, Jackson SP, Wu Q, Mootz HD, Stark JM, Cliff MJ, Schmidt CK. Cabello-Lobato MJ, et al. Among authors: wu q. Nucleic Acids Res. 2022 May 6;50(8):4732-4754. doi: 10.1093/nar/gkac237. Nucleic Acids Res. 2022. PMID: 35420136 Free PMC article.
Dissection of DNA double-strand-break repair using novel single-molecule forceps.
Wang JL, Duboc C, Wu Q, Ochi T, Liang S, Tsutakawa SE, Lees-Miller SP, Nadal M, Tainer JA, Blundell TL, Strick TR. Wang JL, et al. Among authors: wu q. Nat Struct Mol Biol. 2018 Jun;25(6):482-487. doi: 10.1038/s41594-018-0065-1. Epub 2018 May 21. Nat Struct Mol Biol. 2018. PMID: 29786079 Free PMC article.
Mutations in the NHEJ component XRCC4 cause primordial dwarfism.
Murray JE, van der Burg M, IJspeert H, Carroll P, Wu Q, Ochi T, Leitch A, Miller ES, Kysela B, Jawad A, Bottani A, Brancati F, Cappa M, Cormier-Daire V, Deshpande C, Faqeih EA, Graham GE, Ranza E, Blundell TL, Jackson AP, Stewart GS, Bicknell LS. Murray JE, et al. Among authors: wu q. Am J Hum Genet. 2015 Mar 5;96(3):412-24. doi: 10.1016/j.ajhg.2015.01.013. Epub 2015 Feb 26. Am J Hum Genet. 2015. PMID: 25728776 Free PMC article.
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