Willingham SB - Search Results

1

Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.

Li H, Willingham SB, Ting JP, Re F. Li H, et al. Among authors: willingham sb. J Immunol. 2008 Jul 1;181(1):17-21. doi: 10.4049/jimmunol.181.1.17. J Immunol. 2008. PMID: 18566365 Free PMC article.

2

Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome.

Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP. Duncan JA, et al. Among authors: willingham sb. J Immunol. 2009 May 15;182(10):6460-9. doi: 10.4049/jimmunol.0802696. J Immunol. 2009. PMID: 19414800 Free PMC article.

3

NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.

Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, Ting JP. Willingham SB, et al. J Immunol. 2009 Aug 1;183(3):2008-15. doi: 10.4049/jimmunol.0900138. Epub 2009 Jul 8. J Immunol. 2009. PMID: 19587006 Free PMC article.

4

Cutting edge: NLRC5-dependent activation of the inflammasome.

Davis BK, Roberts RA, Huang MT, Willingham SB, Conti BJ, Brickey WJ, Barker BR, Kwan M, Taxman DJ, Accavitti-Loper MA, Duncan JA, Ting JP. Davis BK, et al. Among authors: willingham sb. J Immunol. 2011 Feb 1;186(3):1333-7. doi: 10.4049/jimmunol.1003111. Epub 2010 Dec 29. J Immunol. 2011. PMID: 21191067 Free PMC article.

5

Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.

Willingham SB, Bergstralh DT, O'Connor W, Morrison AC, Taxman DJ, Duncan JA, Barnoy S, Venkatesan MM, Flavell RA, Deshmukh M, Hoffman HM, Ting JP. Willingham SB, et al. Cell Host Microbe. 2007 Sep 13;2(3):147-59. doi: 10.1016/j.chom.2007.07.009. Cell Host Microbe. 2007. PMID: 18005730 Free PMC article.

6

NLRs at the intersection of cell death and immunity.

Ting JP, Willingham SB, Bergstralh DT. Ting JP, et al. Among authors: willingham sb. Nat Rev Immunol. 2008 May;8(5):372-9. doi: 10.1038/nri2296. Nat Rev Immunol. 2008. PMID: 18362948 Review.

7

NLRs and the dangers of pollution and aging.

Willingham SB, Ting JP. Willingham SB, et al. Nat Immunol. 2008 Aug;9(8):831-3. doi: 10.1038/ni0808-831. Nat Immunol. 2008. PMID: 18645588 Free PMC article.

8

Critical role of apoptotic speck protein containing a caspase recruitment domain (ASC) and NLRP3 in causing necrosis and ASC speck formation induced by Porphyromonas gingivalis in human cells.

Huang MT, Taxman DJ, Holley-Guthrie EA, Moore CB, Willingham SB, Madden V, Parsons RK, Featherstone GL, Arnold RR, O'Connor BP, Ting JP. Huang MT, et al. Among authors: willingham sb. J Immunol. 2009 Feb 15;182(4):2395-404. doi: 10.4049/jimmunol.0800909. J Immunol. 2009. PMID: 19201894

9

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling.

Duncan JA, Bergstralh DT, Wang Y, Willingham SB, Ye Z, Zimmermann AG, Ting JP. Duncan JA, et al. Among authors: willingham sb. Proc Natl Acad Sci U S A. 2007 May 8;104(19):8041-6. doi: 10.1073/pnas.0611496104. Epub 2007 May 2. Proc Natl Acad Sci U S A. 2007. PMID: 17483456 Free PMC article.

10

A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer.

Betancur PA, Abraham BJ, Yiu YY, Willingham SB, Khameneh F, Zarnegar M, Kuo AH, McKenna K, Kojima Y, Leeper NJ, Ho P, Gip P, Swigut T, Sherwood RI, Clarke MF, Somlo G, Young RA, Weissman IL. Betancur PA, et al. Among authors: willingham sb. Nat Commun. 2017 Apr 5;8:14802. doi: 10.1038/ncomms14802. Nat Commun. 2017. PMID: 28378740 Free PMC article.

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